Clinical predictors of incipient vertebral fractures and bone mineral density in kidney transplant patients

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dc.authorid0000-0002-5323-2257en_US
dc.authorid0000-0001-7657-3065en_US
dc.contributor.authorYavuz, Dilek Gogas
dc.contributor.authorAydın, Kadriye
dc.contributor.authorApaydın, Tuğçe
dc.contributor.authorVelioğlu, Arzu
dc.contributor.authorMert, Meral
dc.contributor.authorPekkolay, Zafer
dc.contributor.authorAydın, Emre
dc.date.accessioned2023-03-28T12:21:25Z
dc.date.available2023-03-28T12:21:25Z
dc.date.issued2022en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıklar Ana Bilim Dalıen_US
dc.description.abstractPurpose Kidney transplant recipients are prone to metabolic bone diseases and consequent fractures. This study aimed to evaluate the incidence of incipient vertebral fractures, osteopenia, osteoporosis, and the clinical factors associated with incipient vertebral fractures in a group of kidney transplant patients. Methods Two hundred sixty-four patients (F/M 124/140, 45.3 +/- 13 years) who had undergone kidney transplantation in tertiary care centers were included. Vertebral fractures were assessed semiquantitatively using conventional thoracolumbar lateral radiography in 202 of the patients. Results Vertebral fractures were observed in 56.4% (n = 114) of the study group. The frequency of osteoporosis was 20.0% (53 of 264 patients), and osteopenia was 35.6% (94 of 264 patients). Bone mineral density (BMD) levels were in the normal range in 40.3% (n = 46) of the subjects with vertebral fractures. It was in the osteoporotic range in 20.1% (n = 23) and the osteopenic range in 40.3% (n = 46). Vertebral fractures were associated with age, duration of hemodialysis, BMI, and femoral neck Z score (R-2 37.8%, p = 0.027). Conclusion As incipient vertebral fractures can be observed in patients with normal BMD levels in kidney transplant recipients, conventional X-ray screening for vertebral fractures may be beneficial for a proper therapy decision of metabolic bone disease in kidney transplant recipients.en_US
dc.identifier.citationYavuz, D.G., Aydın, K., Apaydın, T., Velioğlu, A., Mert, M., Pekkolay, Z. ve diğerleri. (2022). Clinical predictors of incipient vertebral fractures and bone mineral density in kidney transplant patients. European Spine Journal, 31(9(SI)), 2423-2430.en_US
dc.identifier.doi10.1007/s00586-022-07162-6
dc.identifier.endpage2430en_US
dc.identifier.issn0940-6719
dc.identifier.issn1432-0932
dc.identifier.issue9(SI)en_US
dc.identifier.pmid35376984
dc.identifier.scopus2-s2.0-85127444676
dc.identifier.scopusqualityQ1
dc.identifier.startpage2423en_US
dc.identifier.urihttps://www.authorea.com/users/428998/articles/532765-clinical-predictors-of-incipient-vertebral-fractures-and-bone-mineral-density-in-kidney-transplant-patients?commit=73a1663b4b54202258c04b62adbba18104e7af4e
dc.identifier.urihttps://hdl.handle.net/11468/11543
dc.identifier.volume31en_US
dc.identifier.wosWOS:000778082300002
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorPekkolay, Zafer
dc.institutionauthorAydın, Emre
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Spine Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBone lossen_US
dc.subjectRenal transplantationen_US
dc.subjectSpinal fracturesen_US
dc.subjectOsteopeniaen_US
dc.subjectOsteoporosisen_US
dc.titleClinical predictors of incipient vertebral fractures and bone mineral density in kidney transplant patientsen_US
dc.titleClinical predictors of incipient vertebral fractures and bone mineral density in kidney transplant patients
dc.typeArticleen_US

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