Clinical predictors of incipient vertebral fractures and bone mineral density in kidney transplant patients
Yükleniyor...
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose Kidney transplant recipients are prone to metabolic bone diseases and consequent fractures. This study aimed to evaluate the incidence of incipient vertebral fractures, osteopenia, osteoporosis, and the clinical factors associated with incipient vertebral fractures in a group of kidney transplant patients. Methods Two hundred sixty-four patients (F/M 124/140, 45.3 +/- 13 years) who had undergone kidney transplantation in tertiary care centers were included. Vertebral fractures were assessed semiquantitatively using conventional thoracolumbar lateral radiography in 202 of the patients. Results Vertebral fractures were observed in 56.4% (n = 114) of the study group. The frequency of osteoporosis was 20.0% (53 of 264 patients), and osteopenia was 35.6% (94 of 264 patients). Bone mineral density (BMD) levels were in the normal range in 40.3% (n = 46) of the subjects with vertebral fractures. It was in the osteoporotic range in 20.1% (n = 23) and the osteopenic range in 40.3% (n = 46). Vertebral fractures were associated with age, duration of hemodialysis, BMI, and femoral neck Z score (R-2 37.8%, p = 0.027). Conclusion As incipient vertebral fractures can be observed in patients with normal BMD levels in kidney transplant recipients, conventional X-ray screening for vertebral fractures may be beneficial for a proper therapy decision of metabolic bone disease in kidney transplant recipients.
Açıklama
Anahtar Kelimeler
Bone loss, Renal transplantation, Spinal fractures, Osteopenia, Osteoporosis
Kaynak
European Spine Journal
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
31
Sayı
9(SI)
Künye
Yavuz, D.G., Aydın, K., Apaydın, T., Velioğlu, A., Mert, M., Pekkolay, Z. ve diğerleri. (2022). Clinical predictors of incipient vertebral fractures and bone mineral density in kidney transplant patients. European Spine Journal, 31(9(SI)), 2423-2430.
