Prospective cross-sectional multicenter study on domiciliary noninvasive ventilation in stable hypercapnic COPD patients

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dc.authorid0000-0003-4881-3097en_US
dc.authorid0000-0003-1522-6443en_US
dc.contributor.authorYazar, Esra Ertan
dc.contributor.authorÖzlü, Tevfik
dc.contributor.authorSarıaydın, Muzaffer
dc.contributor.authorTaylan, Mahşuk
dc.contributor.authorEkici, Aydanur
dc.contributor.authorAydın, Derya
dc.contributor.authorCoşgun, İbrahim Güven
dc.date.accessioned2024-01-22T10:50:59Z
dc.date.available2024-01-22T10:50:59Z
dc.date.issued2018en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractBackground: Domiciliary noninvasive ventilation (NIV) use in stable hypercarbic COPD is becoming increasingly widespread. However, treatment compliance criteria and factors related to compliance remain to be defined. Methods: This research was designed as a prospective, cross-sectional, multicenter real-life study. Chronic hypercapnic COPD patients who were using domiciliary NIV for at least 1 year and being followed up in 19 centers across Turkey were included in the study. The patients who used NIV regularly, night or daytime and $5 hours/d, were classified as “high-compliance group,” and patients who used NIV irregularly and ,5 hours/d as “low-compliance group.” Results: Two hundred and sixty-six patients with a mean age of 64.5±10.3 years were enrolled, of whom 75.2% were males. They were using domiciliary NIV for 2.8±2 years. Spontaneous time mode (p,0.001) and night use (p,0.001) were more frequent in the high-compliance group (n=163). Also, mean inspiratory positive airway pressure values of the high-compliance group were significantly higher than the low-compliance group (n=103; p,0.001). Cardiac failure (p=0.049) and obesity (p=0.01) were significantly more frequent in the high-compliance group. There were no difference between 2 groups regarding hospitalization, emergency department and intensive care unit admissions within the last year, as well as modified Medical Research Council dyspnea and COPD Assessment Test scores. With regard to NIV-related side effects, only conjunctivitis was observed more frequently in the high-compliance group (p=0.002). Conclusion: Determination of the patients who have better compliance to domiciliary NIV in COPD may increase the success and effectiveness of treatment. This highly comprehensive study on this topic possesses importance as it suggests that patient and ventilator characteristics may be related to treatment compliance.en_US
dc.identifier.citationYazar, E. E., Özlü, T., Sarıaydın, M., Taylan, M., Ekici, A., Aydın, D. ve diğerleri. (2018). Prospective cross-sectional multicenter study on domiciliary noninvasive ventilation in stable hypercapnic COPD patients. International Journal of COPD, 13, 2367-2374.en_US
dc.identifier.doi10.2147/COPD.S164384
dc.identifier.endpage2374en_US
dc.identifier.issn1176-9106
dc.identifier.pmid30127600
dc.identifier.scopus2-s2.0-85056711616
dc.identifier.scopusqualityQ1
dc.identifier.startpage2367en_US
dc.identifier.urihttps://www.dovepress.com/getfile.php?fileID=43593
dc.identifier.urihttps://hdl.handle.net/11468/13242
dc.identifier.volume13en_US
dc.identifier.wosWOS:000441176100001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTaylan, Mahşuk
dc.language.isoenen_US
dc.publisherDove Medical Press Ltd.en_US
dc.relation.ispartofInternational Journal of COPD
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOPDen_US
dc.subjectNoninvasive ventilationen_US
dc.subjectComplianceen_US
dc.titleProspective cross-sectional multicenter study on domiciliary noninvasive ventilation in stable hypercapnic COPD patientsen_US
dc.titleProspective cross-sectional multicenter study on domiciliary noninvasive ventilation in stable hypercapnic COPD patients
dc.typeArticleen_US

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