Prospective cross-sectional multicenter study on domiciliary noninvasive ventilation in stable hypercapnic COPD patients
Yükleniyor...
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Dove Medical Press Ltd.
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Domiciliary noninvasive ventilation (NIV) use in stable hypercarbic COPD is
becoming increasingly widespread. However, treatment compliance criteria and factors related
to compliance remain to be defined.
Methods: This research was designed as a prospective, cross-sectional, multicenter real-life
study. Chronic hypercapnic COPD patients who were using domiciliary NIV for at least 1 year
and being followed up in 19 centers across Turkey were included in the study. The patients
who used NIV regularly, night or daytime and $5 hours/d, were classified as “high-compliance
group,” and patients who used NIV irregularly and ,5 hours/d as “low-compliance group.”
Results: Two hundred and sixty-six patients with a mean age of 64.5±10.3 years were enrolled,
of whom 75.2% were males. They were using domiciliary NIV for 2.8±2 years. Spontaneous time
mode (p,0.001) and night use (p,0.001) were more frequent in the high-compliance group
(n=163). Also, mean inspiratory positive airway pressure values of the high-compliance group
were significantly higher than the low-compliance group (n=103; p,0.001). Cardiac failure
(p=0.049) and obesity (p=0.01) were significantly more frequent in the high-compliance group.
There were no difference between 2 groups regarding hospitalization, emergency department
and intensive care unit admissions within the last year, as well as modified Medical Research
Council dyspnea and COPD Assessment Test scores. With regard to NIV-related side effects,
only conjunctivitis was observed more frequently in the high-compliance group (p=0.002).
Conclusion: Determination of the patients who have better compliance to domiciliary NIV
in COPD may increase the success and effectiveness of treatment. This highly comprehensive
study on this topic possesses importance as it suggests that patient and ventilator characteristics
may be related to treatment compliance.
Açıklama
Anahtar Kelimeler
COPD, Noninvasive ventilation, Compliance
Kaynak
International Journal of COPD
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
13
Sayı
Künye
Yazar, E. E., Özlü, T., Sarıaydın, M., Taylan, M., Ekici, A., Aydın, D. ve diğerleri. (2018). Prospective cross-sectional multicenter study on domiciliary noninvasive ventilation in stable hypercapnic COPD patients. International Journal of COPD, 13, 2367-2374.
