Biosynthesis, characterization, and biomedical applications of gold nanoparticles with cucurbita moschata duchesne ex poiret peel aqueous extracts

Basit Öğe Kaydı
dc.contributor.authorKaval, Uğur
dc.contributor.authorHoşgören, Hülya
dc.date.accessioned2024-04-24T17:20:52Z
dc.date.available2024-04-24T17:20:52Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn this study, AuNPs were biosynthesized from Cucurbita moschata fruit peel extracts. Biosynthesized AuNPs exhibited maximum absorbance at a 555 nm wavelength, and XRD analysis indicated that the CM-AuNPs had a particle size of less than 100 nm and a cubic crystal structure. TEM scans revealed that the gold particles exhibited a spherical morphology, with an average size of 18.10 nm. FTIR analysis revealed strong peaks indicating the presence of functional groups involved in the reduction reactions. The surface charge of the biosynthesized AuNPs was determined to be -19.7 mV. The antibacterial and antifungal activities of AuNPs against pathogen strains were assessed by the minimum inhibitory concentration (MIC) method. The cytotoxic effects of CM-AuNPs on cancer cell lines (Sk-Ov-3, CaCo2, and A549) and healthy cell lines (HUVEC) were investigated using the MTT method. The findings indicated that AuNPs biosynthesized by the green synthesis method using C. moschata peel aqueous extract had high inhibition on the growth of pathogenic microorganisms and effective cytotoxic activity against cancerous cell lines at low doses. As a result, it can be concluded that CM-AuNPs will be eminently effective in the production of antibacterial and/or anticancer drugs in the pharmaceutical, food, and cosmetic industries.en_US
dc.description.sponsorshipDicle University Scientific Research Projects Coordination Officeen_US
dc.description.sponsorshipThis article was prepared from a Ph.D. dissertation titled Biosynthesis, Characterization and Biomedical Applications of Gold Nanoparticles with Aqueous Extracts of Cucurbita moschata Duchesne Ex Poiret Peel.en_US
dc.identifier.citationKaval, U. ve Hoşgören, H. (2024). Biosynthesis, characterization, and biomedical applications of gold nanoparticles with cucurbita moschata duchesne ex poiret peel aqueous extracts. Molecules, 29(5), 1-18.
dc.identifier.doi10.3390/molecules29050923
dc.identifier.issn1420-3049
dc.identifier.issue5en_US
dc.identifier.pmid38474434
dc.identifier.scopus2-s2.0-85187887571
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.3390/molecules29050923
dc.identifier.urihttps://hdl.handle.net/11468/19284
dc.identifier.volume29en_US
dc.identifier.wosWOS:001183464200001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMolecules
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGreen synthesisen_US
dc.subjectGold nanoparticlesen_US
dc.subjectCucurbita moschataen_US
dc.subjectAntimicrobialen_US
dc.subjectCytotoxic activityen_US
dc.titleBiosynthesis, characterization, and biomedical applications of gold nanoparticles with cucurbita moschata duchesne ex poiret peel aqueous extractsen_US
dc.titleBiosynthesis, characterization, and biomedical applications of gold nanoparticles with cucurbita moschata duchesne ex poiret peel aqueous extracts
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Biosynthesis, Characterization, and Biomedical Applications of Gold Nanoparticles with Cucurbita moschata Duchesne Ex Poiret Peel Aqueous Extracts.pdf
Boyut:
4.03 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Biyoloji Bölümü Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu