Mobile phone exposure does not induce apoptosis on spermatogenesis in rats

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dc.contributor.authorDasdag, Suleyman
dc.contributor.authorAkdag, M. Zulkuf
dc.contributor.authorUlukaya, Engin
dc.contributor.authorUzunlar, Ali Kemal
dc.contributor.authorYegin, Dilek
dc.date.accessioned2024-04-24T16:10:53Z
dc.date.available2024-04-24T16:10:53Z
dc.date.issued2008
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground. Some studies have reported that microwave radiation can have adverse effects on reproduction. Therefore, the purpose of this study was to investigate the apoptosis-inducing effect of mobile phone exposure on spermatogonia in seminiferous tubules. Methods. The study was carried out on 31 Wistar albino adult male rats. The rats were separated into three groups in this study (cage control: 10, sham group: 7, and exposed group: 14). For the study group, rats were exposed to radiation 2 h/day (7 days/week) for 10 months. For the sham group, rats were placed into the carousel and the same procedure was applied except that the generator was turned off. For the cage control, nothing was applied to the rats in this group and they completed their life cycle in the cage during the study period. In this study, rats were sacrificed after 10 months of exposure and their testes were taken. Testes tissue was immunohistochemically stained for the active (cleaved) caspase-3. Positively stained cells were counted in up to ten different areas, and the frequency of positive cells was determined in percentage. Scoring was done by taking into account both the intensity of staining and the distribution of positively stained cells. Therefore, protein expression was evaluated by a serniquantitative scoring system. Results. The final score for apoptosis of testes in the exposed group was not statistically significant according to the sham and the cage control groups (p >0.05). Conclusions. The results of this study showed that 2 h/day (7 days/week) exposure of 900 MHz radiation over a period of 10 months does not affect the active (cleaved) caspase-3 levels in testes, a well-known feature of typical apoptosis. (C) 2008 IMSS. Published by Elsevier Inc.en_US
dc.identifier.doi10.1016/j.arcmed.2007.06.013
dc.identifier.endpage44en_US
dc.identifier.issn0188-4409
dc.identifier.issue1en_US
dc.identifier.pmid18067994en_US
dc.identifier.scopus2-s2.0-36549042004en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage40en_US
dc.identifier.urihttps://doi.org/10.1016/j.arcmed.2007.06.013
dc.identifier.urihttps://hdl.handle.net/11468/15164
dc.identifier.volume39en_US
dc.identifier.wosWOS:000251984000005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofArchives of Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMobile Phoneen_US
dc.subjectApoptosisen_US
dc.subjectCaspase-3en_US
dc.subjectTestesen_US
dc.subjectSeminiferous Tubulesen_US
dc.subjectCellular Phone.en_US
dc.titleMobile phone exposure does not induce apoptosis on spermatogenesis in ratsen_US
dc.typeArticleen_US

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