Mobile phone exposure does not induce apoptosis on spermatogenesis in rats
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Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background. Some studies have reported that microwave radiation can have adverse effects on reproduction. Therefore, the purpose of this study was to investigate the apoptosis-inducing effect of mobile phone exposure on spermatogonia in seminiferous tubules. Methods. The study was carried out on 31 Wistar albino adult male rats. The rats were separated into three groups in this study (cage control: 10, sham group: 7, and exposed group: 14). For the study group, rats were exposed to radiation 2 h/day (7 days/week) for 10 months. For the sham group, rats were placed into the carousel and the same procedure was applied except that the generator was turned off. For the cage control, nothing was applied to the rats in this group and they completed their life cycle in the cage during the study period. In this study, rats were sacrificed after 10 months of exposure and their testes were taken. Testes tissue was immunohistochemically stained for the active (cleaved) caspase-3. Positively stained cells were counted in up to ten different areas, and the frequency of positive cells was determined in percentage. Scoring was done by taking into account both the intensity of staining and the distribution of positively stained cells. Therefore, protein expression was evaluated by a serniquantitative scoring system. Results. The final score for apoptosis of testes in the exposed group was not statistically significant according to the sham and the cage control groups (p >0.05). Conclusions. The results of this study showed that 2 h/day (7 days/week) exposure of 900 MHz radiation over a period of 10 months does not affect the active (cleaved) caspase-3 levels in testes, a well-known feature of typical apoptosis. (C) 2008 IMSS. Published by Elsevier Inc.
Açıklama
Anahtar Kelimeler
Mobile Phone, Apoptosis, Caspase-3, Testes, Seminiferous Tubules, Cellular Phone.
Kaynak
Archives of Medical Research
WoS Q Değeri
Q3
Scopus Q Değeri
N/A
Cilt
39
Sayı
1
