Comparison of antibacterial activity, cytotoxicity, and fluoride release of glass Ionomer restorative dental cements in dentistry

dc.authorid0000-0002-0918-7962en_US
dc.authorid0000-0001-8981-6281en_US
dc.authorid0000-0001-6089-3013en_US
dc.authorid0000-0002-1546-7688en_US
dc.authorid0000-0001-6898-7516en_US
dc.authorid0000-0002-5014-3099en_US
dc.contributor.authorGünay, Ayşe
dc.contributor.authorÇelenk, Sema
dc.contributor.authorAdıgüzel, Özkan
dc.contributor.authorCangül, Suzan
dc.contributor.authorÖzcan, Nida
dc.contributor.authorÇakmakoğlu, Ezgi Eroğlu
dc.date.accessioned2023-08-08T06:47:22Z
dc.date.available2023-08-08T06:47:22Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Diş Hekimliği Fakültesi, Çocuk Diş Hekimliği Bölümüen_US
dc.description.abstractBACKGROUND: This study aimed to compare the antibacterial activity, cytotoxicity, and fluoride release of 4 different glass ionomer cements (GIC). MATERIAL AND METHODS: A total of 200 samples were prepared: Riva Silver, a silver-reinforced GIC; Equia Forte HT, a glass hybrid GIC; ChemFil Rock, a zinc-added GIC; and Ketac™ Molar Easymix. Using the agar diffusion test for antibacterial activity, 30 samples from each group were analyzed for Streptococcus mutans, Lactobacillus acidophilus, and Actinomyces naeslundii. The areas around the samples where no bacterial growth occurred were digitally measured and recorded. For cytotoxicity analysis, the WST-1 test was performed on 10 samples from each group using the L929 mouse fibroblast cell line. The fluoride release property was evaluated using an ion-selective electrode method on 10 samples from each group. RESULTS: The group that used Ketac™ Molar Easymix showed the lowest antibacterial activity against S. mutans, L. acidophilus, and A. naeslundii. In all 3 days of cytotoxicity testing, the group that used Riva Silver was found to be the least toxic material, while the group that used ChemFil Rock did not have viable cells after the 1st day. In all 4 materials, fluoride release values gradually increased since the first day, with Ketac™ Molar Easymix having the highest fluoride release. CONCLUSIONS: Of all the GICs tested, Ketac™ Molar Easymix demonstrated the least antibacterial activity despite having the highest fluoride release, while Riva Silver was found to be the least cytotoxic material.en_US
dc.identifier.citationGünay, A., Çelenk, S., Adıgüzel, Ö., Cangül, S., Özcan, N. ve Çakmakoğlu, E. E. (2023). Comparison of antibacterial activity, cytotoxicity, and fluoride release of glass Ionomer restorative dental cements in dentistry. Medical Science Monitor, (28), 1-8.en_US
dc.identifier.doi10.12659/MSM.939065
dc.identifier.endpage8en_US
dc.identifier.issn1234-1010
dc.identifier.issue28en_US
dc.identifier.pmid36683310
dc.identifier.scopus2-s2.0-85146223665
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.scopus.com/record/display.uri?eid=2-s2.0-85146223665
dc.identifier.urihttps://hdl.handle.net/11468/12448
dc.identifier.wosWOS:000925568400001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGünay, Ayşe
dc.institutionauthorÇelenk, Sema
dc.institutionauthorAdıgüzel, Özkan
dc.institutionauthorCangül, Suzan
dc.institutionauthorÖzcan, Nida
dc.language.isoenen_US
dc.publisherInternational Scientific Informationen_US
dc.relation.ispartofMedical Science Monitor
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFluoridesen_US
dc.subjectGlass Ionomer cementsen_US
dc.subjectAnimalsen_US
dc.subjectMiceen_US
dc.subjectSilveren_US
dc.subjectAnti-bacterial agentsen_US
dc.subjectDental cementsen_US
dc.subjectDentistryen_US
dc.subjectMaterials testingen_US
dc.titleComparison of antibacterial activity, cytotoxicity, and fluoride release of glass Ionomer restorative dental cements in dentistryen_US
dc.titleComparison of antibacterial activity, cytotoxicity, and fluoride release of glass Ionomer restorative dental cements in dentistry
dc.typeArticleen_US

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