Diş Hekimliği Fakültesi Çocuk Diş Hekimliği Anabilim Dalı Koleksiyonu

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https://hdl.handle.net/11468/10468

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Efficacy of mouth rinse formulation based on cetylpyridinium chloride 0.1% in the control of dental calculus buildup
(Innovare Academics Sciences Pvt. Ltd, 2017) Maharani, Diah Ayu; Ramadhani, Alia; Adiatman, Melissa; Wimardhani, Yuniardini Septorini; Kusdhany, Linda; Rahardjo, Anyon; Yavuz, İzzet
Objective: This study aimed at comparing the antiplaque, anticalculus, and antigingivitis potentials of a mouth rinse containing essential oil, alcohol, zinc, and fluoride with a mouth rinse containing cetylpyridinium chloride (CPC) 0.1% over 1-, 2-, and 3-month periods. Methods: This study was a double-blind, parallel randomized clinical trial with a 3-day run-in phase. Respondents were asked to gargle twice daily with 15 ml of mouth rinse for 30 seconds after brushing teeth. Respondents were 80 females with a mean age of 21 years, and a single dental examiner was employed throughout the study to decrease the variance. Prophylaxis was performed for all respondents before the intervention. Three mouth rinses were tested: Group 1 with the mouth rinse containing CPC 0.1%, Group 2 as the negative control, and Group 3 as the positive control with a mouth rinse containing alcohol. Evaluations were conducted by plaque index, gingival index, calculus index, and CariScreen examinations. Results: The clinical trial showed that the mouth rinse with alcohol and the mouth rinse containing CPC 0.1% were effective in inhibiting bacterial buildup (antiplaque) and have anticalculus properties, but with no statistically significant antigingivitis effect. Conclusion: It was found that the mouth rinse containing alcohol has similar effectiveness with CPC 0.1% mouth rinse, but side effects, such as a burning sensation, were reported in the alcohol-containing mouth rinse. © 2017 The Authors. Published by Innovare Academic Sciences Pvt Ltd.
Reliability and accuracy of cone-beam computed tomography voxel density and linear distance measurement at different voxel sizes: A study on sheep head cadaver
(Association for Dental Sciences of the Republic of China, 2017) Güngör, Enes; Doğan, Mehmet Sinan
Background/purpose The reliability and accuracy of linear distance and voxel density (VD) measurements are very important in dentistry. The purpose of this study was to assess the accuracy and reliability of linear distances and VD measurements of cone-beam computed tomography (CBCT) at different voxel sizes. Materials and methods Eighteen-millimeter linears of size 40 gutta-percha were prepared in fresh sheep head. The head was scanned using CBCT with 0.25, 0.3, and 0.40 voxel sizes. Standard linear distances of gutta-percha were measured in panoramic CBCT images at 0.25, 0.3, and 0.4 voxel sizes. VD measurements were made separately on spongeous bone of palatal surfaces of the roots of teeth 4, 5, and 6 of maxilla and on cortical bone of teeth 4, 5, and 6 regions of the left and right hemimandibles through cross-sectional imaging. Results We found that linear distance measurements on panoramic image of CBCT were slightly lower than physical measurements. A significant difference was not found for the gutta-percha linear distances and cortical VD measurements at different voxel sizes (P ≥ 0.05). The correlation between measurements of VD at different voxels in cortical bone was greater than 0.85 (P = 0.000). Conclusion Linear distance measurements on the sheep head cadaver of 0.25, 0.3, and 0.4 voxel sizes were similar and reliable when compared with physical measurements. In minimizing radiation exposure, VD measurement of cortical bone at 0.4 voxel-based CBCT could be used to estimate cortical bone density. However, studies should be performed on the human head cadaver.
Genetic landscape of congenital insensitivity to pain and hereditary sensory and autonomic neuropathies
(2023) Lischka, Annette; Eggermann, Katja; Record, Christopher J.; Dohrn, Maike F.; Laššuthová, Petra; Kraft, Florian; Bolgül, Behiye Sezgin
Congenital insensitivity to pain (CIP) and hereditary sensory and autonomic neuropathies (HSAN) are clinically and genetically heterogeneous disorders exclusively or predominantly affecting the sensory and autonomic neurons. Due to the rarity of the diseases and findings based mainly on single case reports or small case series, knowledge about these disorders is limited. Here, we describe the molecular workup of a large international cohort of CIP/HSAN patients including patients from normally under-represented countries. We identify 80 previously unreported pathogenic or likely pathogenic variants in a total of 73 families in the >20 known CIP/HSAN-associated genes. The data expand the spectrum of disease-relevant alterations in CIP/HSAN, including novel variants in previously rarely recognized entities such as ATL3-, FLVCR1- and NGF-associated neuropathies and previously under-recognized mutation types such as larger deletions. In silico predictions, heterologous expression studies, segregation analyses and metabolic tests helped to overcome limitations of current variant classification schemes that often fail to categorize a variant as disease-related or benign. The study sheds light on the genetic causes and disease-relevant changes within individual genes in CIP/HSAN. This is becoming increasingly important with emerging clinical trials investigating subtype or gene-specific treatment strategies.
Saliva analysis in children with active caries before and after dental treatment
(Universitas Airlangga, Faculty of Dental Medicine, 2022) Akleyin, Ebru; Sarıyıldız, Cansu Osmanoğulları; Yavuz, İzzet; Toptancı, İsmet Rezani
Background: The amount and quality of saliva play important roles in maintaining an intraoral bacterial balance. The quality of saliva is defined by its buffering capacity, viscosity, pH and protein content. The amount of saliva is usually related to the flow rate. Purpose: This study aimed to compare the flow rate, pH, viscosity and buffering capacity of saliva as well as plaque formation in children before and after dental treatment. Methods: Saliva samples were taken from paediatric patients before their treatments and one month after their dental treatments had ended, and these saliva samples were then analysed. For each sample analysis, the GC Saliva-Check Buffer kit (GC Corporation, Tokyo, Japan) was used to evaluate buffering capacity, pH and flow rate, and the GC Saliva-Check Mutans kit (GC Corporation, Tokyo, Japan) was used for the determination of Streptococcus Mutans. GC Tri Plaque ID gel (GC Corporation, Tokyo, Japan) was applied to evaluate plaque maturation. Results: The pre-treatment buffering capacity, pH and viscosity sample values were found to be significantly lower than the post-treatment values (p[removed]0.05). When examining plaque maturation, it was determined that all of the post-treatment plaque was pink. Conclusion: This study showed that the pH, viscosity and buffering capacity of saliva had increased significantly post-treatment and that the formation of plaque had decreased in children with active caries after all their dental treatments had been completed.
Knowledge and attitudes of a group of dental students in Turkey about molar incisor hypomineralization
(International Scientific Information, Inc., 2023) Günay, Ayşe
Background: This study aimed to evaluate the knowledge and attitudes of 4th- and 5th-year students of Dicle University Faculty of Dentistry (Diyarbakır) about molar incisor hypomineralization (MIH). Material/Methods: The questionnaires previously used in other countries were modified and the questionnaire forms consisting of 23 questions were distributed to the students online. The results of the analysis are presented as frequencies. The significance level was set as P<0.05. Results: A total of 111 4th-year students (51%) and 107 5th-year students (49%) participated in our study. A statistically significant difference was found between the 4th-year students (68.5%) and the 5th-year students (98.1%) in terms of having heard of the term MIH before (P<0.001). While most students reported knowing the clinical features of MIH, only 26.1% were confident in their diagnosis. A statistically significant difference was found between the 4th- and 5th-year students who thought that MIH was a clinical problem, in the distribution of those who had problems both in terms of aesthetics, and in providing adequate restoration (P=0.012). Conclusions: Although most of the students were theoretically familiar with MIH, they were not confident in their diagnosis and found it difficult to differentiate MIH from other dental anomalies. However, the awareness of 5th-year dental students was better than that of the 4th-year students.
Reasons for requesting cone-beam computed tomography in children and adolescents: a 10-year study
(Taylor and Francis Ltd., 2022) Akleyin, Ebru; Eskibağlar, Büşra Karaağaç
Analysis of the reasons for requesting dental cone-beam computed tomography (CBCT) in children and adolescents can provide new evidence to guidelines developed specifically to protect patients from potential harmful effects of ionizing radiation. This retrospective study aimed to determine the reasons for requesting dental CBCT in paediatric patients. We included all patients aged <18 years who underwent CBCT between 2011 and 2021 at the Dentomaxillofacial Radiology Department of Dicle University Dental Faculty. Out of 8214 archived records in total, 1619 CBCT request forms of paediatric patients were examined. These forms provided the data on each participant’s age, gender, requesting department, the reason for the request, and year of the request. We evaluated 762 males and 857 females; 0.68% were aged 4–5 years, 27.55% were 6–11 years, and 71.77% were 12–17 years. The requests for CBCT were made by the Orthodontics Department in 61.4% of cases and by the Surgical Department in 25.82% of cases. The most common indication for CBCT (33.42% of cases) was to determine the presence of embedded teeth. We found a significant correlation between the age group and indications (p < 0.05). The age group of children and adolescents for whom CBCT was requested most often was the 12–17 years age group. In conclusion, the most common indication for CBCT was to determine the presence of embedded teeth in orthodontics. The rate of use of CBCT in the diagnosis and treatment of paediatric patients in dentistry has increased in the last decade.
Travmatik diş yaralanmalarında ilkokul öğretmenlerinin bilgi düzeyleri ve tutumlarının belirlenmesi ve öğretmenlere verilen öğretici broşürün etkisinin değerlendirilmesi
(Yeditepe Üniversitesi Diş Hekimliği Fakültesi, 2017) Şimşek, İbrahim; Ayna, Buket; Uysal, Ersin
Amaç: Diyarbakır ilinde görev yapan ilkokul öğretmenlerinin travmatik diş yaralanmaları (TDY) karşısındaki tutumlarının ve kişisel tecrübelerinin değerlendirilmesi, bilgi düzeylerinin ölçülmesi ve hazırlanan öğretici broşürlerle, öğretmenlere diş yaralanmalarının ardından yapacakları ilk müdahalelerle dişin iyileşme sürecine katkı sağlayabilecekleri bilincinin yerleştirilmesidir. Gereç ve yöntem: Çalışmamıza Diyarbakır il merkezindeki 34 ilkokulda görev yapmakta olan 1224 ilkokul öğretmeni dahil edilmiştir. Katılımcı öğretmenlere dört bölümden oluşan TDY konusunda sorular içeren anket formaları dağıtılıp cevaplamaları istenmiştir. Anket sorularının cevaplanması bittikten sonra öğretmenlerin konu hakkındaki bilgi seviyesini arttırmak amacıyla hazırladığımız öğretici broşürler teslim edilmiş ve iki hafta sonra öğretmenlerin aynı anket sorularını tekrar cevaplamaları sağlanmıştır. Bulgular: Öğretmenlere yöneltilen anket sonucunda 1. bölümde katılımcı öğretmenlerin kişisel bilgileri değerlendirilmiştir. Cinsiyetin, yaşın ve meslekte hizmet süresinin bilgi düzeyini etkilediği görülmüştür. Bilgi düzeyinin uygulanan öğretici broşürün etkisi ile her parametrede anlamlı bir şekilde arttığı tespit edilmiştir. İkinci bölümde öğretmenlerin TDY karşısındaki tutumları değerlendirilmek istenmiş ve öğretici broşürlerin etkisi ile alınan cevaplarda anlamlı bir farklılık olduğu görülmüştür. Kişisel tecrübe ve kendini değerlendirme başlıklı 3. bölümde öğretmenlerin %60’ı daha önce diş yaralanması gördüğünü belirtmiştir ve görülen bu yaralanmaların %36,7’sinin küçük bir kırık olduğu öğrenilmiştir. Katılımcı öğretmenlerin %48,6’sı TDY sonrası ilk başvuracakları birimi “Diş hastanesi” cevabı ile belirtmişlerdir. TDY’deki bilgi düzeyini ölçmeyi amaçlayan 4. bölümde ise öğretici broşürlerin etkisi ile tüm vaka değerlendirmelerinde bilgi düzeyinde anlamlı bir artış gözlemlenirken sadece süt dişi avülsiyonuna yönelik yöneltilen soru için anlamlı bir farklılık gözlenmemiştir. Sonuç: Çalışmanın sonuçları değerlendirildiğinde elde edilen veriler Diyarbakır’daki ilkokul öğretmenlerinin TDY konusundaki bilgi düzeylerinin hazırlanan broşürler öncesinde yeterli olmadığını göstermektedir. Bununla birlikte öğretici broşürlerin etkisi ile elde edilen sonuçlar ümit vericidir.
Çocuklarda daimi birinci büyük azı dişlerinin kontrollü çekimi
(Yeditepe Üniversitesi Diş Hekimliği Fakültesi, 2021) Eskibağlar, Büşra Karaağaç; Ayna, Buket
Daimi birinci büyük azı (DBBA) dişleri; daimi dişlenmeye ait okluzyonun sağlanmasında kilit rol üstlenmekte, çiğneme fonksiyonuna önemli derecede katkısı olmakta ve diğer dişlerin sürmesinde rehber görevi görmektedir. Bununla birlikte, DBBA dişleri çürük nedeniyle en sık kaybedilen ve çürüğe en yatkın olan dişlerdir. Bu dişlerin kontrolsüz çekilmesi pek çok olumsuz duruma sebep olmaktadır. Uygun zaman ve doğru oklüzyon koşullarında daimi birinci büyük azı dişlerinin kontrollü çekilmesi hastanın ortodontik tedavi ihtiyacını minimuma indirecektir. Bu derlemede; kötü prognozlu daimi birinci büyük azı dişlerinin kontrollü çekim prosedürleri anlatılarak, ideal oklüzyonu sağlamak için gerekli olan faktörler belirtilmiştir
Türkiye’deki preklinik diş hekimliği öğrencilerinin dental travma konusundaki bilgi düzeylerinin değerlendirilmesi
(Mersin Üniversitesi Sağlık Bilimleri Enstitüsü, 2023) Acartürk, Musa; Günay, Ayşe
Amaç: Literatürde; ebeveynlerin, öğretmenlerin, diş hekimliği ve tıp fakültesi öğrencilerinin dental travma ile ilgili farkındalıklarını değerlendiren çalışmalar bulunmaktadır. Ancak, farklı üniversitelerdeki preklinik (birinci ve ikinci sınıf) öğrencilerinin bu konudaki farkındalıklarını değerlendiren kapsamlı bir çalışmaya henüz rastlanmamıştır. Bu çalışma, dental travma konusunda teorik ve pratik eğitim almamış diş hekimliği fakültesi preklinik öğrencilerinin dental travma ile ilgili bilgi düzeylerini değerlendirmeyi amaçlamaktadır. Yöntem: Türkiye’deki diş hekimliği fakültelerinin birinci ve ikinci sınıf öğrencilerine yönelik hazırlanan 15 soruluk anket formu, daha önceden kullanılmış olan anketler modifiye edilerek oluşturulmuştur. Çalışma için gerekli gözlem sayısının belirlenmesi amacıyla güç (power) analizi yapılmıştır. Anket sorularının cevapları yüzde olarak hesaplanmış ve verilerin analizinde ki-kare testi kullanılmıştır. Anlamlılık düzeyi α=0.05 olarak belirlenmiştir. Bulgular: Çalışmaya, sekiz farklı diş hekimliği fakültesinden toplam 586 öğrenci katılmıştır. Öğrencilerin çoğunluğu (%90.4) dental travma konusunda yeterli bilgiye sahip olmadığını belirtmiştir. Kendisini yeterli bulan öğrencilerin %55.4’ü ise diş hekimleri üzerinden bilgilendiklerini ifade etmiştir. Preklinik öğrencilerinin; %85.2’si travma sonrası avülse olan dişlerin steril serum fizyolojik ile yıkanıp tekrar yerine yerleştirilmesi gerektiğini, %38.6’sı ise avülse dişlerin soketine yerleştirilememesi durumunda steril serum fizyolojik içerisinde muhafaza edilerek diş hekimine götürülmesi gerektiğini belirtmiştir. Sonuç: Anket sonuçları değerlendirildiğinde, preklinik diş hekimliği öğrencileri genel itibariyle doğru yaklaşımlar sergilemiştir. Ancak, bazı sorular hakkında eksik ve yanlış bilgilere sahip oldukları saptanmıştır.
Estudio clínico y molecular en una familia con displasia cleidocraneal
(Sociedad Argentina de Pediatria, 2017) Callea, Michele; Fattori, Fabiana; Bertini, Enrico Silvio; Yavuz, İzzet; Bellacchio, Emanuele; Avendaño, Andrea
Cleidocranial dysplasia is an uncommon bone dysplasia with an autosomal dominant inheritance pattern characterized by short stature, large fontanels, midface hypoplasia, absence or hypoplasia of clavicles and orodental alterations. This is produced by mutations in the RUNX2 gene located at 6p21.1. We report two male adolescents (cousins), with cleidocranial dysplasia who presented a heterozygous missense mutation (c.674G>A, p.R225Q) in the RUNX2 gene, characterized by severe phenotype, such as absent clavicles, but with variation in the delayed fontanel closure, dental abnormalities (anomalies in shape and number) and scoliosis, thus demonstrating intrafamilial variation in these patients with the same genotype.
Comparison of antibacterial activity, cytotoxicity, and fluoride release of glass Ionomer restorative dental cements in dentistry
(International Scientific Information, 2023) Günay, Ayşe; Çelenk, Sema; Adıgüzel, Özkan; Cangül, Suzan; Özcan, Nida; Çakmakoğlu, Ezgi Eroğlu
BACKGROUND: This study aimed to compare the antibacterial activity, cytotoxicity, and fluoride release of 4 different glass ionomer cements (GIC). MATERIAL AND METHODS: A total of 200 samples were prepared: Riva Silver, a silver-reinforced GIC; Equia Forte HT, a glass hybrid GIC; ChemFil Rock, a zinc-added GIC; and Ketac™ Molar Easymix. Using the agar diffusion test for antibacterial activity, 30 samples from each group were analyzed for Streptococcus mutans, Lactobacillus acidophilus, and Actinomyces naeslundii. The areas around the samples where no bacterial growth occurred were digitally measured and recorded. For cytotoxicity analysis, the WST-1 test was performed on 10 samples from each group using the L929 mouse fibroblast cell line. The fluoride release property was evaluated using an ion-selective electrode method on 10 samples from each group. RESULTS: The group that used Ketac™ Molar Easymix showed the lowest antibacterial activity against S. mutans, L. acidophilus, and A. naeslundii. In all 3 days of cytotoxicity testing, the group that used Riva Silver was found to be the least toxic material, while the group that used ChemFil Rock did not have viable cells after the 1st day. In all 4 materials, fluoride release values gradually increased since the first day, with Ketac™ Molar Easymix having the highest fluoride release. CONCLUSIONS: Of all the GICs tested, Ketac™ Molar Easymix demonstrated the least antibacterial activity despite having the highest fluoride release, while Riva Silver was found to be the least cytotoxic material.
Evaluation of radiation exposure due to dental radiographs taken during endodontic treatment sessions in young permanent teeth
(MDPI, 2022) Akleyin, Ebru; Yavuz, Yasemin
Background and Objectives: The aim of this study was to retrospectively analyze the duration of treatment and the number of dental radiographs taken during endodontic treatment (endo-t) of young permanent teeth (YPT). Materials and Methods: Age, gender, affected tooth number, apex status, duration of treatment and dental radiographs taken during this period were retrospectively evaluated in pediatric patients aged 6–15 years who presented to the pedodontic department for endo-t of anterior YPT. Data were analyzed with Kruskal Wallis H, Dunn and Pearson chi-square tests. p < 0.05 was accepted as statistically significant in all analyses. Results: Anterior endo-t was initiated in 471 of 9,200 pedodontic patients between the ages of 6 and 15 years who applied to our university. The reason for seeking treatment was caries (8.1%) and trauma (91.9%). It was observed that 59% of the teeth had an open apex and 45.7% had a closed apex. A total of 1893 periapical radiographs (Per-R) and 245 panoramic radiographs (Pan-R) were taken from 471 pediatric patients during the treatment period. Total number of dental radiographs was 2138 with 4.5 per patient. Number of Per-R was lower in patients whose treatment was completed in a single session (p < 0.001). There was no difference in the number of Pan-R with respect to duration of treatment (p = 0.560). Conclusions: In children, the number of Per-R significantly increased with prolonged duration of treatment encompassing multiple sessions for endo-t procedures of anterior YPT, decided based on the apex and lesion status of the affected tooth. Especially in long-term traditional apexification treatments, treatment should be carried out in children with the ALADAIP (As Low As Diagnostically Achievable being Indication-oriented and Patient-specific) principle in mind.
13-16 yaş grubu çocuklarda panoramik radyografide diş durumlarının değerlendirilmesi
(Yeditepe Üniversitesi Diş Hekimliği Fakültesi, 2023) Çakmakoğlu, Ezgi Eroğlu; Günay, Ayşe
Amaç: Çocuk diş hekimliği kliniklerinde, panoramik radyog- rafi (PR) kullanımı çekilen radyografiler arasında ilk sırayı al- maktadır. Ayrıca, PR'ler sürmüş ve sürmemiş dişler, diş germ- leri ve diş anormallikleri gibi konularda dentomaksillofasiyal bölge hakkında bilgi sağlamaktadır. Bizim çalışmamızın ama- cı, PR’ler üzerinden peg shaped dişler, ikiz dişler, kaynaşma, birleşme, diş içinde diş ve dilaserasyon görülme sıklıklarını tespit etmek ve bunlara ek olarak bu anomalilere sahip olan ve olmayan dişlerdeki çürükleri, dolguları, çekimleri, kanal te- davilerini değerlendirmektir. Gereç ve Yöntem: 13-16 yaş aralığındaki çocuk hastalardan her yaş grubu için rastgele seçilen toplamda 4060 PR incelen- miştir. İncelenen PR’de dişlerdeki çürükler, dolgular, çekimler, kanal tedavileri, peg shaped dişler, ikiz diş, kaynaşma, birleş- me, diş içinde diş ve dilaserasyonlar tespit edilmiştir. Bu bilgi- lere yaş ve cinsiyet demografik verileri de eklenip incelemeye alınmıştır. Bulgular: İncelenen biçim anomalilerinin her birinin görülme sıklığı diş içinde diş %0,02 (1), birleşme %0,07 (3), ikiz diş %0,02 (1), kaynaşma %0,42 (17), peg shaped dişler %3,87 (157), dila- serasyon %4,36 (177) olarak bulunmuştur. Çalışmaya katılan- lardan 332 (%8,17) kişide en az bir gelişimsel dental anomali görülmekteyken; 3728 kişide hiçbir anomali bulunmamakta- dır. Herhangi bir anomalisi olmayanların dolgulu diş sayısı en az bir anomalisi olanlara göre anlamlı derecede düşüktür. Sonuç: Panoramik radyografi arşivinden faydalanılarak yapı- lan bu çalışmada, elde edilen veriler sayesinde dental anoma- li prevalansının az olmadığı ve dental anomalinin dolgulu diş sayısını arttırdığı tespit edilmiştir.
Accuracy of four different apex locators in primary molars: An in vitro study
(Türkiye Klinikleri Yayınevi, 2023) Akleyin, Ebru; Özata, Merve Yeniçeri; Kaya, Sadullah
Objective: The aim of this study is to compare and evaluate the accuracy of 4 different electronic apex locators (EALs) (Root ZX Mini, Raypex 6, Propex Pixi, and E-Pex Pro) in primary molars with and without root resorption. Material and Methods: Forty-eight mandibular primary molar teeth with (24 teeth) and without (24 teeth) physiological root resorption, each with 4 root canals, were included in the study (96 canals in with resorption group and 96 canals in without resorption group) (n=192 root canals). The actual working length (AWL) was determined by subtracting 0.5 mm from the measured length for each canal. The differences between AWL and electronic working length readings of the 4 EALs and accuracy rates within specified tolerance intervals (TI; ±0.5 and ±1.0 mm) were calculated. Results: The presence of resorption in the teeth significantly affected the measurement using Root ZX Mini (p<0.05). In teeth without resorption, all EALs yielded an accuracy rate of 100% at ±1.0 mm TI, whereas the accuracy rates ranged from 91.7% to 95.8% at ±0.5 mm TI. In teeth with resorption, EALs yielded accuracy rates of 74.0%-65.6% at ±1.0 mm TI and 52.1%- 60.4% at ±0.5 mm TI. Conclusion: At ±0.5 mm TI, Raypex 6 had greater accuracy in teeth without root resorption, whereas Propex Pixi had greater accuracy in teeth with root resorption. Apex locator preference may vary depending on the presence or absence of resorption.
Clinical and radiological findings, SEM analysis and evaluation of caries risk in ectodermal dysplasia cases
(Taylor & Francis, 2022) Yavuz, Yasemin; Akleyin, Ebru; Akdağ, Mehmet Zülküf; Çolak, Mehmet; Doğan, Mehmet Sinan; Kotanlı, Sedef
Ectodermal dysplasia (ED) consists of many different combinations of irregularities that include developmental defects that occur in two or more of the following tissues: teeth, nails, skin, hair and sweat glands. The aim of this study was to evaluate the possible carries risk, perform scanning electron microscopy (SEM) mineral analysis in ectodermal dysplasia cases and describe the oral aspects. Ectodermal dysplasia cases, 41 patients (22 males and 19 females, aged 1.5 to 45 years), had a clinical examination. SEM analyses were performed from teeth that had to be extracted from ED cases for various reasons. Forty-one patients had tooth agenesis (from hypodontia to anodontia), multiple caries, hair and nail dystrophy. Also, extra orally they had sparse or absent hair, a short face, an unusual facial concavity, maxillary retrusion and relative mandibular protrusion. Differences between tooth samples were determined by SEM analyses. SEM analyses showed that the mineral content of ED teeth was lower than that of normal teeth and the surface properties of dentin and enamel were different. It is necessarily to support this observation with more comprehensive research. When dentists examine ED patients, they should consider the oral mucosa for excessive dryness and increased dental caries and should conduct a comprehensive, multidisciplinary approach to these patients in order to improve their dental, masticatory and caries conditions.
Ektodermal displazili olgularda klinik ve radyolojik bulguların incelenmesi
(Fırat Üniversitesi Tıp Fakültesi, 2019) Doğan, Mehmet Sinan; Ataş, Osman; Yavuz, İzzet; Tekin, Samet
Amaç: Ektodermal displazi; deri, tırnak, saç, ter bezleri ve diş gibi ektoderm kaynaklı dokuları etkileyen ve nadir olarak rastlanan kalıtsal bir hastalıktır. Bu çalışmada fakülte hastanemize başvuran ektodermal displazili olgulardaki; sistemik ve dental bulguların klinik ve radyolojik olarak değerlendirilmesi amaçlanmıştır.Gereç ve Yöntem: Çalışmamızda 2006-2017 yılları arasında Dicle Üniversitesi Diş Hekimliği Fakültesi hastanesine diş eksikliği şikayetiyle başvuran, 49 ektodermal displazi olgusu retrospektif olarak değerlendirildi. Klinik değerlendirmede saç, tırnak, deri, diş, burun, ter bezleri ve benzeri malformasyonlar incelendi. Radyolojik muayenede; geleneksel radyografi ve konik ışınlı bilgisayarlı tomografi kullanılarak diş germleri, çene kemiği vediş köklerine bakıldı.Bulgular: Çalışmamızda yaş ortalaması 11,9±4,6 olan, 25’i kadın (%51,1), 24’ü erkek (%48,9) toplam 49 hasta değerlendirildi. Çalışmadaki ED’lihastaların oral bulguları ile ilgili olarak; %100 (n =49) diş eksikliği, %100 (n =49) mandibular protrüzyon ,%75,51 (n =37) konik diş, %6,12 (n =3)kök şekil anomalileri görülmüştür. Klinik muayenesinde ise terleme problemi %77.55 (n =38), saç-kıl anomalisi %95.91 (n =47), anormal parmak vetırnaklar %83.67 (n =41) belirlendi.Sonuç: ED’nin temel bulguları oral ve maksillofasiyal bölgede oluştuğundan, estetik ve çiğneme problemleri ortaya çıkmaktadır. Bu nedenle dişhekimliğinde multidisipliner tedavi gerektiren özel bir yere sahiptir. Bu hastalarda yaşam kalitesini artırmaya yönelik olarak tıp ve diş hekimlerininkoordineli çalışması oldukça önem kazanmaktadır.
Ectodermal dysplasia: A retrospective evaluation of the clinical findings of forty-four cases in the 0-16 years age
(Uluslararası Diş Araştırmaları Birliği, 2022) Akleyin, Ebru; Sarıyıldız, Cansu Osmanoğulları; Yavuz, İzzet; Adıgüzel, Özkan
Aim: The aim of this study was to review the craniofacial anomaly results of children diagnosed with ectodermal dysplasia (ED) and to identify the oral requirements of ED cases. Methodology: The data of this study were obtained by taking clinical examinations and radiographs on forty-four (44) children (22 females and 22 males), 0-16 years aged, who were admitted to the Dicle University, Faculty of Dentistry due to dental problems and were diagnosed with ED. The number of affected siblings was ascertained, and systemic findings were evaluated. Malformations in the hair, nails, nose, skin, lips, and teeth were clinically examined. Results: The most common clinical findings were sparse hair, dry skin, sweating problems, respiratory difficulty, saddle nose, a history of fever, hearing loss, and deformation in the nails. In the intraoral and radiological examinations, findings were evaluated of conical teeth, protuberant lips, prosthetic rehabilitation, impacted teeth, and abnormal root resorption. The rates of ED in the siblings of the ED cases were determined as 39.2% in the siblings of male cases and 37.9% in the siblings of female cases. Conclusion: The frequency rates of the anomalies seen in ED obtained in this study can be considered important as a guide for further studies of individuals with ED. When multiple missing teeth and conical teeth are encountered, the dental practitioner should investigate whether or not there are other symptoms of ED, and it must not be forgotten that the dentist may be the first step in the diagnosis of this genetic irregularity.
Microleakage of two different posterior composites and a high-viscosity glass-ionomer cement: An in vitro study
(Uluslararası Diş Araştırmaları Birliği, 2022) Çelenk, Sema; Ayna, Buket; Ataş, Osman; Günay, Ayşe
Aim: Using AutoCAD, we examined the microleakage of permanent molars in Class I restorations using a conventional posterior composite resin, a bulk-fill composite resin, and a high-viscosity glass-ionomer cement (HVGIC). Methodology: In total, 33 extracted noncarious third molars were used. Class I cavities were prepared. The teeth were randomly divided into three groups of 11 teeth each, as follows: Group A (Filtek Z550), Group B (Filtek Bulk-Fill Posterior Restorative), and Group C (EQUIA Fil). All specimens were stored for 24 h at 37 °C in distilled water. The teeth were thermocycled 1,000 times between 5 ± 2C and 55 ± 2°C prior to immersion in 0.5% basic fuchsin for 24 h. Two mesiodistal cuts of each tooth were photographed under a stereomicroscope equipped with a digital camera. The dye-infiltrated surface area was measured. Results: Statistical evaluations were performed by one-way analysis of variance [ANOVA]. One-way ANOVA showed no significant difference between the three groups in microleakage (P = 0.07). However, the lowest microleakage ratio was seen in Group C (EQUIA Fil). Similar results were obtained with all tested materials, but the lowest microleakage rate was obtained with EQUIA Fil (Group C). Conclusion: In this study, the tested materials were not completely successful in eliminating microleakage, although the lowest microleakage rate was obtained with EQUIA Fil.
Volumetric pulp chambers measurements in mandibular and maxillary permanent first molar using cone-beam computed tomography by age and gender
(Uluslararası Diş Araştırmaları Birliği, 2019) Kavas, Anıl Açıklar; Tümen, Emin Caner
Aim: The aim of this study was to demonstrate the anatomical structureof pulp chamber, measure the volume of the total pulp chambers in mm3and evaluate the pulp chamber volume changes by age and genderstatistically in mandibular and maxillary first molars by means of CBCT.Methodology: In our study, CBCT examinations of patients between theages of 7-18 years, which were carried out due to different reasons wereevaluated retrospectively. The CBCT images of healthy total of 160 lowerand upper right permanent first molar teeth were selected randomly andthe volumes of the total pulp chamber were measured in mm3 with the 3DSlicer software program. We analyzed the collected data with statisticalanalysis methods and we evaluated whether there was any differencebetween the patients grouped according to the age in respect of volumechanges in the total pulp chamber and whether there was any differencebetween the mean volume values and gender of the patients within thesame group.Results: Comparison of the volume measurements of the lower and upperfirst permanent molar teeth between the groups showed that the volumevalues of the total pulp chamber decreased depending on the age (p<0.05).Regarding gender, volume decrease related to age was statistically moresignificant among females. We determined in all age groups except age 7-9 group that the volume value of the total pulp chamber of the upperpermanent first molar teeth was statistically higher than the volume valueof the total pulp chamber of the lower permanent first molar teeth(p<0,05).Conclusions: We believe that CBCT is an easy and conservative methodfor the 3D-imaging of the pulp chamber, volume measurement andexamination of the dimensional changes of the total pulp chamberdepending on deposition of secondary dentin.
Evaluation of the effectiveness of remineralization preparations used in paediatric dentistry practices
(Uluslararası Diş Araştırmaları Birliği, 2019) Tatar, Emine; Toptancı, İsmet Rezani
Aim: The goal of this particular research was to scrutinize theremineralization effects of fluoride varnish, casein phosphopeptideamorphous calcium phosphates (CPP-ACP) and casein phosphopeptideamorphous calcium fluoride phosphates (CPP-ACFP) cream, andtricalcium phosphate (TCP) varnish.Methodology: The study was designed as an experimental researchwhereby samples with early artificial caries lesions were randomlydivided into the following 5 groups with 20 samples in each group: (I)control, (II) fluoride varnish, (III) CPP-ACP cream, (IV) CPP-ACFP creamand (V) TCP varnish. The effectiveness of these remineralization agentswas evaluated using a laser fluorescence device (DIAGNOdent), a scanningelectron microscope (SEM) and energy dispersive X-ray analysis (EDX).Results: In the pre- and post-treatment evaluations, the DIAGNOdentremineralization measurements were statistically significant in all thegroups, except the control group (p < 0.05). In comparison with theDIAGNOdent measurements, the CPP-ACFP group was found to havesignificantly higher remineralization than the fluoride group (p < 0.05),while no significant differences were found between the other groups (p> 0.05). The EDX analysis evaluated the Ca/P ratio between the groups.These results indicated that the CPP-ACFP group was significantly higherthan the control group, the CPP-ACP group and the TCP group (p < 0.05);no significant differences were found between the CPP-ACFP group andthe fluoride group (p > 0.05). In SEM imaging, the most extensive mineralaccumulation was observed in the CPP-ACFP group.Conclusions: Three analytical methods demonstrated that CPP-ACFPwas the most effective remineralization material tested in this study.

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