Protective effectiveness of anise against testicular ischemia and reperfusion injury: An experimental study in rats

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dc.authorid0000-0002-1659-1189en_US
dc.authorid0000-0001-9843-6301en_US
dc.authorid0000-0002-6384-9146en_US
dc.authorid0000-0001-6453-0033en_US
dc.authorid0000-0002-5799-3985en_US
dc.contributor.authorYıldızhan, Eda
dc.contributor.authorAkkuş, Murat
dc.contributor.authorÜlger, Burak Veli
dc.contributor.authorAşır, Fırat
dc.contributor.authorSöker, Sevda
dc.contributor.authorGündüz, Ercan
dc.contributor.authorRençber, M.
dc.contributor.authorBarçin, Mahsum
dc.date.accessioned2023-08-15T08:07:26Z
dc.date.available2023-08-15T08:07:26Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalıen_US
dc.description.abstractTesticular torsion is a frequently encountered clinical condition that requires urgent treatment. The aim of this study is to investigate the efficacy of Anise (Pimpinella anisum L.) in treating the pathological condition due to ischemia and reperfusion injury by using biochemical, histopathological and immunohistochemical methods. A total of 6 groups were formed with 8 male Wistar Albino rats in each group. Group 1 (n=8): control group, Group 2 (n=8): Anise aqueous solution was given orally 5 ml/kg by gavage for 30 days. Group 3 (n=8): Ischemia and Reperfusion (I/R) group, bilateral testicles were rotated 270° and reperfused after 30 minutes of ischemia. Group 4 (n=8): I/R+ Anise group, Group 5 (n=8): Anise+ I/R group and Group 6 (n=8): Anise+ I/R+ Anise group. The results of the Anise group and the Control group were similar. However, the damage in the I/R group was considerably more severe than in any of the other study groups. While it was observed that spermatogenic cells started to regenerate in the I/R+Anise group, edema and congestion were observed in the Anise+I/R group. In the Anise+I/R+Anise group, all histological findings and biochemical parameters were similar to those of the control group. It was observed that anise had protective effects in ischemia and reperfusion injury in rat testicles.en_US
dc.identifier.citationYıldızhan, E., Akkuş, M., Ülger, B. V., Aşır, F., Söker, S., Gündüz, E. ve diğerleri. (2023). Protective effectiveness of anise against testicular ischemia and reperfusion injury: An experimental study in rats. Polish Journal of Veterinary Sciences, 26(2), 249-255.en_US
dc.identifier.doi10.24425/pjvs.2023.145029
dc.identifier.endpage255en_US
dc.identifier.issn1505-1773
dc.identifier.issue2en_US
dc.identifier.pmid37389431
dc.identifier.scopus2-s2.0-85164232814
dc.identifier.scopusqualityQ3
dc.identifier.startpage249en_US
dc.identifier.urihttps://journals.pan.pl/dlibra/publication/145029/edition/127678/content
dc.identifier.urihttps://hdl.handle.net/11468/12477
dc.identifier.volume26en_US
dc.identifier.wosWOS:001023483300009
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYıldızhan, Eda
dc.institutionauthorAkkuş, Murat
dc.institutionauthorÜlger, Burak Veli
dc.institutionauthorAşır, Fırat
dc.institutionauthorSöker, Sevda
dc.institutionauthorGündüz, Ercan
dc.institutionauthorBarçin, Mahsum
dc.language.isoenen_US
dc.publisherPolska Akademia Nauken_US
dc.relation.ispartofPolish Journal of Veterinary Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAniseen_US
dc.subjectTesticleen_US
dc.subjectIschemiaen_US
dc.subjectReperfusionen_US
dc.subjectImmunohistochemistryen_US
dc.titleProtective effectiveness of anise against testicular ischemia and reperfusion injury: An experimental study in ratsen_US
dc.titleProtective effectiveness of anise against testicular ischemia and reperfusion injury: An experimental study in rats
dc.typeArticleen_US

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