Effect of Ramadan fasting on platelet aggregation in healthy male subjects

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dc.contributor.authorAybak, M
dc.contributor.authorTurkoglu, A
dc.contributor.authorSermet, A
dc.contributor.authorDenli, O
dc.date.accessioned2024-04-24T15:59:35Z
dc.date.available2024-04-24T15:59:35Z
dc.date.issued1996
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe purpose of this study was to examine platelet aggregation during Ramadan fasting. A group of 20 healthy non-smoking male volunteers were studied, whose mean age was [21 (SD 2.4) years range 19-24]. The average fast was about 15 h. Venous blood samples were taken on 4 different days; 1 day before Ramadan (day 0), then on the 1st, 14th and 28th day of Ramadan, On each of these 4 days, blood samples were taken at 4 p.m. (1 h before the evening meal). Body mass index and platelet count did nor change during fasting. Bleeding and coagulation time had increased significantly by the end of Ramadan fasting (P < 0.05, P < 0.005 respectively), but these changes remained within physiological Limits. Ramadan fasting induced a reduction in platelet sensitivity to adenosine 5'-diphosphate (ADP) and collagen on days 14 (P < 0.05) and 28 (P < 0.05, P < 0.005 respectively). However, adrenaline-induced. platelet aggregation decreased only on day 25 (P < 0.05). This study indicated that Ramadan fasting led to a decrease in the platelet responses of different aggregating agents (ADP, adrenaline and collagen) in vitro. It also led to an increase in bleeding and coagulation time.en_US
dc.identifier.doi10.1007/BF00357678
dc.identifier.endpage556en_US
dc.identifier.issn1439-6319
dc.identifier.issn1439-6327
dc.identifier.issue6en_US
dc.identifier.pmid8817126
dc.identifier.scopus2-s2.0-0030017820
dc.identifier.scopusqualityQ1
dc.identifier.startpage552en_US
dc.identifier.urihttps://doi.org/10.1007/BF00357678
dc.identifier.urihttps://hdl.handle.net/11468/14161
dc.identifier.volume73en_US
dc.identifier.wosWOS:A1996UV76100009
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Journal of Applied Physiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRamadan Fastingen_US
dc.subjectPlatelet Aggregationen_US
dc.subjectBlood Lipidsen_US
dc.subjectGlucoseen_US
dc.titleEffect of Ramadan fasting on platelet aggregation in healthy male subjectsen_US
dc.titleEffect of Ramadan fasting on platelet aggregation in healthy male subjects
dc.typeArticleen_US

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