Global longitudinal strain score predicts all cause death in patients with chronic total occlusion with preserved ejection fraction

dc.authorid0000-0003-2243-6190en_US
dc.authorid0000-0003-4326-6418en_US
dc.authorid0000-0002-9049-7123en_US
dc.authorid0000-0002-4169-0592en_US
dc.authorid0000-0003-1860-6513en_US
dc.authorid0000-0001-7317-2979en_US
dc.contributor.authorÖzbek, Mehmet
dc.contributor.authorBilik, Mehmet Zihni
dc.contributor.authorDemir, Muhammed
dc.contributor.authorArık, Baran
dc.contributor.authorŞimşek, Hakkı
dc.contributor.authorErtaş, Faruk
dc.contributor.authorToprak, Nizamettin
dc.date.accessioned2024-03-19T12:21:23Z
dc.date.available2024-03-19T12:21:23Z
dc.date.issued2022en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractOBJECTIVE: Change in LVEF is one of the most important indicators of prognosis in CTO cases. Studies in patients with CTO have shown improvement in LVEF approximately at 3 and 6 months after successful PCI. It has been shown that LV global longitudinal strain (GLS) starts to improve even 1 day after CTOPCI. We aimed at investigating the effect of subclinical echocardiographic involvement on allcause mortality in the group with CTO and preserved ejection fraction by evaluating the LV GLS score. PATIENTS AND METHODS: Patients with LVEF ≥ 50% were considered to have preserved ejection fraction and were included in the study. The endpoint of the study was all-cause death. For this retrospective study, 1,171 patients with coronary angiography who had had CTO in any of their vessels were screened. RESULTS: A total of 86 consecutive patients were reviewed in the study. The optimum GLS score cut-off value (≥ 14.18) for predicting mortality was determined using receiver operating characteristic (ROC) curve analysis (AUC: 0.897, sensitivity 87.5%, specificity 81.5% p<0.001). At a mean follow-up of 49 months, a significant difference was found between the two groups in all-cause mortality determined by the GLS score [2 (3.4%) vs. 14 (51.9%), p<0.001]. A significant difference in mortality was observed between the group with a low GLS score and the group with a high GLS score, according to Kaplan-Meier analysis. The effect of GLS score in predicting all-cause mortality was demonstrated in multivariate cox regression analysis (Low GLS score; OR: 6.36 95%CI (1.039-39.013), p=0.045). Cox regression multivariate analysis and the effect of GLS score in predicting mortality were observed [Low GLS score; OR: 6.368 95%CI (1.039-39.013), p=0.045]. CONCLUSIONS: As a predictor, GLS may be a valuable marker of cardiac subclinical dysfunction for all caused mortality in CTO patients.en_US
dc.identifier.citationÖzbek, M., Bilik, M. Z., Demir, M., Arık, B., Şimşek, H., Ertaş, F. ve diğerleri. (2022). Global longitudinal strain score predicts all cause death in patients with chronic total occlusion with preserved ejection fraction. European Review for Medical and Pharmacological Sciences, 26(17), 6251-6258.en_US
dc.identifier.doi10.26355/eurrev_202209_29648
dc.identifier.endpage6258en_US
dc.identifier.issn1128-3602
dc.identifier.issue17en_US
dc.identifier.pmid36111926
dc.identifier.scopus2-s2.0-85138226269
dc.identifier.scopusqualityQ2
dc.identifier.startpage6251en_US
dc.identifier.urihttps://www.europeanreview.org/wp/wp-content/uploads/6251-6258.pdf
dc.identifier.urihttps://hdl.handle.net/11468/13636
dc.identifier.volume26en_US
dc.identifier.wosWOS:000860601000029
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzbek, Mehmet
dc.institutionauthorBilik, Mehmet Zihni
dc.institutionauthorDemir, Muhammed
dc.institutionauthorArık, Baran
dc.institutionauthorŞimşek, Hakkı
dc.institutionauthorErtaş, Faruk
dc.institutionauthorToprak, Nizamettin
dc.language.isoenen_US
dc.publisherVerduci Editore s.r.len_US
dc.relation.ispartofEuropean Review for Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic total occlusionen_US
dc.subjectGLSen_US
dc.subjectStrain echocardiographyen_US
dc.titleGlobal longitudinal strain score predicts all cause death in patients with chronic total occlusion with preserved ejection fractionen_US
dc.titleGlobal longitudinal strain score predicts all cause death in patients with chronic total occlusion with preserved ejection fraction
dc.typeArticleen_US

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