Global longitudinal strain score predicts all cause death in patients with chronic total occlusion with preserved ejection fraction
Yükleniyor...
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Verduci Editore s.r.l
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
OBJECTIVE: Change in LVEF is
one of the most important indicators of prognosis in CTO cases. Studies in patients with CTO
have shown improvement in LVEF approximately at 3 and 6 months after successful PCI. It has
been shown that LV global longitudinal strain
(GLS) starts to improve even 1 day after CTOPCI. We aimed at investigating the effect of subclinical echocardiographic involvement on allcause mortality in the group with CTO and preserved ejection fraction by evaluating the LV
GLS score.
PATIENTS AND METHODS: Patients with LVEF
≥ 50% were considered to have preserved ejection
fraction and were included in the study. The endpoint of the study was all-cause death. For this retrospective study, 1,171 patients with coronary angiography who had had CTO in any of their vessels were screened.
RESULTS: A total of 86 consecutive patients
were reviewed in the study. The optimum GLS
score cut-off value (≥ 14.18) for predicting mortality was determined using receiver operating
characteristic (ROC) curve analysis (AUC: 0.897,
sensitivity 87.5%, specificity 81.5% p<0.001). At
a mean follow-up of 49 months, a significant
difference was found between the two groups
in all-cause mortality determined by the GLS
score [2 (3.4%) vs. 14 (51.9%), p<0.001]. A significant difference in mortality was observed
between the group with a low GLS score and
the group with a high GLS score, according to
Kaplan-Meier analysis. The effect of GLS score
in predicting all-cause mortality was demonstrated in multivariate cox regression analysis
(Low GLS score; OR: 6.36 95%CI (1.039-39.013),
p=0.045). Cox regression multivariate analysis
and the effect of GLS score in predicting mortality were observed [Low GLS score; OR: 6.368
95%CI (1.039-39.013), p=0.045].
CONCLUSIONS: As a predictor, GLS may be a
valuable marker of cardiac subclinical dysfunction
for all caused mortality in CTO patients.
Açıklama
Anahtar Kelimeler
Chronic total occlusion, GLS, Strain echocardiography
Kaynak
European Review for Medical and Pharmacological Sciences
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
26
Sayı
17
Künye
Özbek, M., Bilik, M. Z., Demir, M., Arık, B., Şimşek, H., Ertaş, F. ve diğerleri. (2022). Global longitudinal strain score predicts all cause death in patients with chronic total occlusion with preserved ejection fraction. European Review for Medical and Pharmacological Sciences, 26(17), 6251-6258.
