Craniofacial Characteristics of Thalassemia Major Patients

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dc.contributor.authorKarakas, Sacide
dc.contributor.authorTellioglu, Ayfer Metin
dc.contributor.authorBilgin, Mehmet
dc.contributor.authorOmurlu, Imran Kurt
dc.contributor.authorCaliskan, Sercin
dc.contributor.authorCoskun, Salih
dc.date.accessioned2024-04-24T17:27:27Z
dc.date.available2024-04-24T17:27:27Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Thalassemias major are the most common autosomal recessive disorders; they are characterized by anomalies in the synthesis of the beta chains of hemoglobin and are often associated with varying degrees of craniofacial anomalies. The purpose of this study was to evaluate the craniofacial dimensions of beta-thalassemia patients and to identify differences by comparing them to those of a control group. Materials and Methods: The study comprised 43 thalassemia major patients and 26 age-and sex-matched healthy control subjects. Anthropometric measurements were performed in six different craniofacial regions (head, face, nose, mouth, eyes, and ears); a total of 23 craniofacial variables were measured. Results: Craniofacial measurements in the regions of the face, nose, lips and mouth, and ears in the thalassemia major patient group yielded statistically significant differences compared to those in the control group (p<0.05). However, no statistically significant differences were observed in the measurements of the head and eye regions. Conclusion: The study increased our understanding of the craniofacial anatomy of thalassemia major patients and enabled us to obtain quantitative results.en_US
dc.description.sponsorshipAdnan Menderes University, Aydin, Turkey [TPF- 10039]en_US
dc.description.sponsorshipThis work was supported by a grant from Adnan Menderes University, Aydin, Turkey (through grant no. TPF- 10039).en_US
dc.identifier.doi10.5152/eurasianjmed.2016.150013
dc.identifier.endpage208en_US
dc.identifier.issn1308-8734
dc.identifier.issn1308-8742
dc.identifier.issue3en_US
dc.identifier.pmid28149147
dc.identifier.scopus2-s2.0-85010194123
dc.identifier.scopusqualityQ2
dc.identifier.startpage204en_US
dc.identifier.trdizinid215836
dc.identifier.urihttps://doi.org/10.5152/eurasianjmed.2016.150013
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/215836
dc.identifier.urihttps://hdl.handle.net/11468/19946
dc.identifier.volume48en_US
dc.identifier.wosWOS:000392738300011
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofEurasian Journal of Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectThalassemia Majoren_US
dc.subjectCraniofacial Measurementsen_US
dc.subjectTurkeyen_US
dc.titleCraniofacial Characteristics of Thalassemia Major Patientsen_US
dc.titleCraniofacial Characteristics of Thalassemia Major Patients
dc.typeArticleen_US

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