Systemic inflammation in both open-angle and angle-closure glaucoma: role of platelet-to-lymphocyte ratio

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dc.authorid0000-0002-3591-721Xen_US
dc.contributor.authorKarahan, M.
dc.contributor.authorKılıç, D.
dc.contributor.authorGüven, S.
dc.date.accessioned2022-07-07T12:25:11Z
dc.date.available2022-07-07T12:25:11Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.descriptionWOS:000637614800006
dc.descriptionPMID: 33393320
dc.description.abstractAIM: To analyse the effect of systemic infl ammatory status in patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) by calculating platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR). METHODS: This retrospective case-control study included 200 patients with POAG, 22 patients with PACG and 100 healthy subjects. The participants' white-blood-cell, lymphocyte, neutrophil, and platelet counts were recorded from previous blood assays. NLR and PLR were calculated manually. Results were compared among the groups. RESULTS: Both the POAG and PACG groups had higher platelet counts and PLR values than the control group (p=0.001 and p=0.001; respectively). The difference in NLR between POAG, PACG and control groups was not statistically signifi cant (p=0.076). The POAG group had higher NLR values than the control (p=0.035). CONCLUSION: Both the POAG and the PACG groups exhibited higher platelet and PLR levels than the control. These results indicate a potential role of systemic infl ammation in the pathogenesis of POAG and PACG (Tab. 4, Fig. 1, Ref. 35). Text in PDF www.elis.sken_US
dc.identifier.citationKarahan, M., Kılıç, D.ve Güven, S. (2021). Systemic inflammation in both open-angle and angle-closure glaucoma: role of platelet-to-lymphocyte ratio. Bratislava Medical Journal- Bratislavske Lekarske Listy, 122(1), 45-48. http://doi.org/10.4149/BLL_2021_005en_US
dc.identifier.doi10.4149/BLL_2021_005
dc.identifier.endpage48en_US
dc.identifier.issn0006-9248
dc.identifier.issn1336-0345
dc.identifier.issue1en_US
dc.identifier.pmid33393320
dc.identifier.scopus2-s2.0-85099271190
dc.identifier.scopusqualityQ2
dc.identifier.startpage45en_US
dc.identifier.urihttp://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=7057&category_id=171&option=com_virtuemart&vmcchk=1&Itemid=1
dc.identifier.urihttps://hdl.handle.net/11468/10144
dc.identifier.volume122en_US
dc.identifier.wosWOS:000637614800006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKarahan, Mine
dc.language.isoenen_US
dc.publisherAepress Sroen_US
dc.relation.ispartofBratislava Medical Journal- Bratislavske Lekarske Listy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectNeutrophil-to-lymphocyte ratioen_US
dc.subjectPlatelet-to-lymphocyte-ratioen_US
dc.subjectPrimary open-angle glaucomaen_US
dc.subjectPrimary angle-closure glaucomaen_US
dc.subjectSystemic inflammationen_US
dc.titleSystemic inflammation in both open-angle and angle-closure glaucoma: role of platelet-to-lymphocyte ratioen_US
dc.titleSystemic inflammation in both open-angle and angle-closure glaucoma: role of platelet-to-lymphocyte ratio
dc.typeArticleen_US

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