Systemic inflammation in both open-angle and angle-closure glaucoma: role of platelet-to-lymphocyte ratio
Yükleniyor...
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Aepress Sro
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
AIM: To analyse the effect of systemic infl ammatory status in patients with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) by calculating platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR).
METHODS: This retrospective case-control study included 200 patients with POAG, 22 patients with PACG and 100 healthy subjects. The participants' white-blood-cell, lymphocyte, neutrophil, and platelet counts were recorded from previous blood assays. NLR and PLR were calculated manually. Results were compared among the groups.
RESULTS: Both the POAG and PACG groups had higher platelet counts and PLR values than the control group (p=0.001 and p=0.001; respectively). The difference in NLR between POAG, PACG and control groups was not statistically signifi cant (p=0.076). The POAG group had higher NLR values than the control (p=0.035).
CONCLUSION: Both the POAG and the PACG groups exhibited higher platelet and PLR levels than the control. These results indicate a potential role of systemic infl ammation in the pathogenesis of POAG and PACG (Tab. 4, Fig. 1, Ref. 35). Text in PDF www.elis.sk
Açıklama
WOS:000637614800006
PMID: 33393320
PMID: 33393320
Anahtar Kelimeler
Neutrophil-to-lymphocyte ratio, Platelet-to-lymphocyte-ratio, Primary open-angle glaucoma, Primary angle-closure glaucoma, Systemic inflammation
Kaynak
Bratislava Medical Journal- Bratislavske Lekarske Listy
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
122
Sayı
1
Künye
Karahan, M., Kılıç, D.ve Güven, S. (2021). Systemic inflammation in both open-angle and angle-closure glaucoma: role of platelet-to-lymphocyte ratio. Bratislava Medical Journal- Bratislavske Lekarske Listy, 122(1), 45-48. http://doi.org/10.4149/BLL_2021_005
