An Evaluation of Nitric Oxide, Folate, Homocysteine Levels and Lipid Peroxidation in Postmenopausal Osteoporosis

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dc.contributor.authorAkpolat, Veysi
dc.contributor.authorBilgin, H. Murat
dc.contributor.authorCelik, M. Yusuf
dc.contributor.authorErdemoglu, Mahmut
dc.contributor.authorIsik, Birgul
dc.date.accessioned2024-04-24T17:33:14Z
dc.date.available2024-04-24T17:33:14Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjectives. In the current study, the risk coefficients of nitric oxide (NO), folate, homocysteine levels and lipid peroxidation in postmenopausal osteoporotic women were determined. Material and Methods. Bone mineral density was determined by dual-energy X-ray absorptiometry. The levels of serum lipid peroxidation products such as the thiobarbituric acid adduct of malondialdehyde (MDA) were measured spectrophotometrically. Plasma folate and homocysteine (Hcy) levels were measured by enzyme chemiluminescence immunoassay. Plasma nitrite levels were measured with the Griess reaction Results. The odds ratios and 95% Confidence Intervals (CI) of the variables MDA, folate, NO, body-mass index (BMI), menopause age and age were found significant. MDA, NO and folate variables were found statistically significant in the analysis of receiver operating charecteristic (ROCs). The areas under the curve (AUCs, 95% CI) of MDA, NO and folate were found to be statistically significant. Conclusions. The current study indicates that NO, MDA and folate are risk variables for postmenopausal osteoporosisen_US
dc.identifier.endpage409en_US
dc.identifier.issn1899-5276
dc.identifier.issn2451-2680
dc.identifier.issue3en_US
dc.identifier.pmid23828682
dc.identifier.scopus2-s2.0-84881363850
dc.identifier.scopusqualityQ1
dc.identifier.startpage403en_US
dc.identifier.urihttps://hdl.handle.net/11468/20549
dc.identifier.volume22en_US
dc.identifier.wosWOS:000324350800013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWroclaw Medical Univen_US
dc.relation.ispartofAdvances in Clinical and Experimental Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNitric Oxideen_US
dc.subjectFolateen_US
dc.subjectMalondialdehydeen_US
dc.subjectHomocysteineen_US
dc.subjectOsteoporosisen_US
dc.titleAn Evaluation of Nitric Oxide, Folate, Homocysteine Levels and Lipid Peroxidation in Postmenopausal Osteoporosisen_US
dc.titleAn Evaluation of Nitric Oxide, Folate, Homocysteine Levels and Lipid Peroxidation in Postmenopausal Osteoporosis
dc.typeArticleen_US

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