Asthma phenotypes in Turkey: a multicenter cross-sectional study in adult asthmatics; PHENOTURK study

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dc.contributor.authorYildiz, Fusun
dc.contributor.authorMungan, Dilsad
dc.contributor.authorGemicioglu, Bilun
dc.contributor.authorYorgancioglu, Arzu
dc.contributor.authorDursun, Berna
dc.contributor.authorErkekol, Ferda Oner
dc.contributor.authorOgus, Candan
dc.date.accessioned2024-04-24T17:11:26Z
dc.date.available2024-04-24T17:11:26Z
dc.date.issued2017
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground and AimsTo evaluate asthma phenotypes in patients with asthma from different regions of Turkey. MethodsA total of 1400 adult asthmatic patients (mean (SD) age: 44.0 (13.9) years, 75% females) from 14 centers across Turkey were included in this study and a standard questionnaire was applied between the time period of February 2011-January 2012. ResultsThe disease onset40 years of age was higher percentage in obese vs. normal/overweight patients and nonallergic vs. allergic patients (P<0.01). The percentage of patients who had FEV1 values over 80% was higher in allergic than nonallergic and normal/overweight than obese patients (P<0.01). Uncontrolled asthmatics have more severe disease (P<0.01). There were more frequent hospital admissions in nonallergic and uncontrolled asthmatics (P<0.01). Chronic rhino-sinusitis was the leading comorbid disorder in normal/overweight and allergic asthma, while gastroesophageal reflux disorder was more frequent in nonallergic and uncontrolled asthma (P<0.01). Asthma control rate was the highest (39.0%) in patients from Marmara region among all geographical regions (P<0.05). ConclusionIn conclusion, our findings revealed existence of clinical/trigger related phenotypes based on BMI, allergic status, control level and geographical region with more frequent respiratory dysfunction and/or adverse health outcomes in uncontrolled, obese and nonallergic phenotypes.en_US
dc.description.sponsorshipTurkish Thoracic Society, Asthma-Allergy Working Groupen_US
dc.description.sponsorshipThis study was funded by the Turkish Thoracic Society, Asthma-Allergy Working Group. We would also like to thank KAPPA Consultancy Training Research Ltd, Istanbul for providing editorial support and Alpha Medical, Istanbul for providing support in statistical analysis.en_US
dc.identifier.doi10.1111/crj.12326
dc.identifier.endpage223en_US
dc.identifier.issn1752-6981
dc.identifier.issn1752-699X
dc.identifier.issue2en_US
dc.identifier.pmid26073091
dc.identifier.scopus2-s2.0-84935457011
dc.identifier.scopusqualityQ3
dc.identifier.startpage210en_US
dc.identifier.urihttps://doi.org/10.1111/crj.12326
dc.identifier.urihttps://hdl.handle.net/11468/17516
dc.identifier.volume11en_US
dc.identifier.wosWOS:000395446700009
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofClinical Respiratory Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAllergy-Asthma-Control Level-Disease Onset-Obesity-Phenotypes-Severityen_US
dc.titleAsthma phenotypes in Turkey: a multicenter cross-sectional study in adult asthmatics; PHENOTURK studyen_US
dc.titleAsthma phenotypes in Turkey: a multicenter cross-sectional study in adult asthmatics; PHENOTURK study
dc.typeArticleen_US

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