Obstructive sleep apnoea, cigarette smoking and serum testosterone levels in a male sleep clinic cohort

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dc.contributor.authorKirbas, G.
dc.contributor.authorAbakay, A.
dc.contributor.authorTopcu, F.
dc.contributor.authorKaplan, A.
dc.contributor.authorUnlu, M.
dc.contributor.authorPeker, Y.
dc.date.accessioned2024-04-24T17:14:42Z
dc.date.available2024-04-24T17:14:42Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractThis study evaluated the impact of obstructive sleep apnoea (OSA) and smoking on total serum testosterone levels in 96 men (mean age 43.3 years; range 25 - 60 years) attending a sleep clinic. Fifty-five men (57.3%) had OSA, defined as an apnoea-hypopnoea index of 2: 15 events/h, recorded during overnight polysomnography, and 42 (43.8%) were current smokers. Mean serum total testosterone levels were significantly lower in OSA subjects (3.4 ng/ml) than in non-OSA subjects (3.9 ng/ml), whereas no significant difference was observed between current smokers and nonsmokers. In a multiple linear regression analysis, serum testosterone was negatively correlated with body mass index and the apnoea-hypopnoea index, but not with age and pack-years of smoking. Our results support previous observations regarding testosterone levels in men with OSA, but, contrary to some earlier reports, there was no positive relationship between smoking and total testosterone in the present cohort.en_US
dc.identifier.doi10.1177/147323000703500103
dc.identifier.endpage45en_US
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue1en_US
dc.identifier.pmid17408053
dc.identifier.scopus2-s2.0-33947588354
dc.identifier.scopusqualityQ2
dc.identifier.startpage38en_US
dc.identifier.urihttps://doi.org/10.1177/147323000703500103
dc.identifier.urihttps://hdl.handle.net/11468/18148
dc.identifier.volume35en_US
dc.identifier.wosWOS:000245339300003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal of International Medical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectObstructive Sleep Apnoeaen_US
dc.subjectHypogonadismen_US
dc.subjectSmokingen_US
dc.subjectTestosteroneen_US
dc.titleObstructive sleep apnoea, cigarette smoking and serum testosterone levels in a male sleep clinic cohorten_US
dc.titleObstructive sleep apnoea, cigarette smoking and serum testosterone levels in a male sleep clinic cohort
dc.typeReview Articleen_US

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