Relationships Between Respiratory Function Disorders and Serum Copper Levels in Copper Mineworkers
[ X ]
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Humana Press Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
The aim of this study was to investigate the respiratory function disorders that could be related to dust exposure during the production of copper mine in copper mineworkers (CMWs). The study included 75 male CMWs (mean age, 32.0 +/- 7.1 years, 58.6% smokers) and 75 male age- and smoking status-matched healthy control subjects. Serum Cu level was significantly higher in the CMW group (0.80 +/- 0.62 mu g/ml) than the control group (0.60 +/- 0.39 mu g/ml) (p = 0.017). Significant negative correlations were found between serum Cu level and forced expiratory volume in first second (r = -0.600; p < 0.001) and between serum Cu level and forced vital capacity (r = -0.593; p = < 0.001) in CMWs. Serum Cu level was significantly higher in the restrictive type pulmonary function disorders group (1.36 +/- 0.62 mu g/ml) than obstructive type (0.90 +/- 0.55 mu g/ml) and normal pulmonary function pattern group (0.53 +/- 0.43 mu g/ml) (p < 0.001). Patients with radiological parenchymal abnormalities had significantly higher serum copper levels than those without abnormalities (1.53 +/- 0.52 vs. 0.71 +/- 0.52 mu g/ml, respectively; p = 0.002). In conclusion, result of the study has shown a negative association between pulmonary functions disorders and radiological abnormalities and serum Cu levels in CMWs.
Açıklama
Anahtar Kelimeler
Copper, Respiratory Function, Copper Mineworkers
Kaynak
Biological Trace Element Research
WoS Q Değeri
Q4
Scopus Q Değeri
Q1
Cilt
145
Sayı
2
