Mean Platelet Volume in Patients with Nonarteritic Anterior Ischemic Optic Neuropathy

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dc.contributor.authorSahin, Muhammed
dc.contributor.authorSahin, Alparslan
dc.contributor.authorElbey, Bilal
dc.contributor.authorYuksel, Harun
dc.contributor.authorTurkcu, Fatih Mehmet
dc.contributor.authorCingu, Abdullah Kursat
dc.date.accessioned2024-04-24T17:12:15Z
dc.date.available2024-04-24T17:12:15Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective. We aimed to investigate the mean platelet volume (MPV) of the patients with nonarteritic anterior ischemic optic neuropathy (NAION). Methods. The medical records of 46 patients with the diagnosis of NAION and 90 control subjects were retrospectively evaluated. All participants underwent complete ocular examination including intraocular pressure (IOP) measurement. Hematocrit, MPV, hemoglobin, and platelet levels of the patients with NAION were compared with those of control subjects. Results. There was no significant difference between the groups in platelet counts (p = 0.76). NAION group had significantly higherMPV values (8.25 +/- 1.26 fL) than that of control subjects (7.64 +/- 1.01 fL) (p < 0.001). Multivariate logistic regression analysis showed that MPV is an independent predictor of NAION (odds ratio = 1.61; 95% confidence interval (CI) = 1.13-2.28; p = 0.007). The mean IOP was significantly higher in NAION group (p < 0.001). IOP was also found as an independent predictor of NAION according to the regression analysis (OR = 1.27; 95% CI = 1.08-1.48; p = 0.003). Conclusion. Our results demonstrated that the MPV values were significantly higher in NAION patients, suggesting that larger platelets may contribute to the pathogenesis of the NAION.en_US
dc.description.sponsorshipDicle University DUBAPen_US
dc.description.sponsorshipThe authors are grateful to Dicle University DUBAP for their sponsorship of English editing of this paper and are grateful to Yilmaz Palanci, M. D., Department of Public Health, Dicle University School of Medicine, for statistical analysis.en_US
dc.identifier.doi10.1155/2016/1051572
dc.identifier.issn2090-004X
dc.identifier.issn2090-0058
dc.identifier.pmid26966556en_US
dc.identifier.scopus2-s2.0-84959377726en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1155/2016/1051572
dc.identifier.urihttps://hdl.handle.net/11468/17908
dc.identifier.volume2016en_US
dc.identifier.wosWOS:000370271600001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofJournal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keyword]en_US
dc.titleMean Platelet Volume in Patients with Nonarteritic Anterior Ischemic Optic Neuropathyen_US
dc.typeArticleen_US

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