The effect of extremely low frequency magnetic field on the conjunctiva and goblet cells

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dc.contributor.authorKeklikci, Ugur
dc.contributor.authorAkpolat, Veysi
dc.contributor.authorOzekinci, Selver
dc.contributor.authorUnlu, Kaan
dc.contributor.authorCelik, M. Salih
dc.date.accessioned2024-04-24T16:24:32Z
dc.date.available2024-04-24T16:24:32Z
dc.date.issued2008
dc.departmentDicle Üniversitesien_US
dc.description.abstractPurpose: The aim of this study was to examine the effects of extremely low frequency magnetic field (ELF MF) on the conjunctiva and goblet cells density. Methods: Thirty adult female Spraque Dawley rats were assigned to one of two groups, each containing 15 rats. The experimental group received magnetic field 4 hr/day for 7 days. The second group received standard laboratory care and served as a control. The specimens were evaluated by light microscopy for goblet cell density, conjunctival edema, inflammation, and fibroblast proliferation. Results: In ELF MF exposure group rats, the number of goblet cells was less than the control group. We also observed a significant difference between ELF MF exposure group and control group in terms of goblet cell density (p = 0.010). The ELF MF exposure group manifested conjunctival edema and inflammation compared to the control group (p < 0.001 and p = 0.003). There was no statistical difference between the groups for fibroblast proliferation (p = 0.422). Conclusion: This study suggests that ELF MF exposure leads to morphological alterations of the conjunctiva and reductions in the number of goblet cells. We believe that ELF MF may cause dry eye symptoms.en_US
dc.identifier.doi10.1080/02713680802074867
dc.identifier.endpage446en_US
dc.identifier.issn0271-3683
dc.identifier.issn1460-2202
dc.identifier.issue5-6en_US
dc.identifier.pmid18568881
dc.identifier.scopus2-s2.0-47349111085
dc.identifier.scopusqualityQ1
dc.identifier.startpage441en_US
dc.identifier.urihttps://doi.org/10.1080/02713680802074867
dc.identifier.urihttps://hdl.handle.net/11468/16758
dc.identifier.volume33en_US
dc.identifier.wosWOS:000256672100005
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofCurrent Eye Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectConjunctivaen_US
dc.subjectElectromagnetic Fielden_US
dc.subjectGoblet Cellen_US
dc.subjectInflammationen_US
dc.subjectRaten_US
dc.titleThe effect of extremely low frequency magnetic field on the conjunctiva and goblet cellsen_US
dc.titleThe effect of extremely low frequency magnetic field on the conjunctiva and goblet cells
dc.typeArticleen_US

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