Paraoxonase Activity and Oxidative Status in Patients with Tinnitus

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dc.contributor.authorKoc, Sema
dc.contributor.authorAkyuz, Servet
dc.contributor.authorSomuk, Battal Tahsin
dc.contributor.authorSoyalic, Harun
dc.contributor.authorYilmaz, Beyhan
dc.contributor.authorTaskin, Abdullah
dc.contributor.authorBilinc, Hasan
dc.date.accessioned2024-04-24T17:33:08Z
dc.date.available2024-04-24T17:33:08Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground and Objectives: The aim of this study was to investigate serum paraoxanase-1 (PON) activity, total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) in tinnitus; and to compare the results with data from healthy subjects. Subjects and Methods: A total of 114 subjects-54 patients with tinnitus and 60 healthy controls were enrolled in this study. Serum PON activity, TOS, TAS, and OSI levels were measured. Results: In the tinnitus group, TAS, and PON were significantly lower than in the control group (p<0.001). However, the TOS, and OSI levels were significantly higher in the tinnitus group than in the control group (p<0.001). Conclusions: According to the data obtained from the present study, patients with tinnitus were exposed to potent oxidative stress. Oxidative stress may be the key contributing factor to the pathogenesis of tinnitus.en_US
dc.identifier.doi10.7874/jao.2016.20.1.17
dc.identifier.endpage21en_US
dc.identifier.issn2384-1621
dc.identifier.issn2384-1710
dc.identifier.issue1en_US
dc.identifier.pmid27144229
dc.identifier.scopus2-s2.0-84965037237
dc.identifier.scopusqualityQ3
dc.identifier.startpage17en_US
dc.identifier.urihttps://doi.org/10.7874/jao.2016.20.1.17
dc.identifier.urihttps://hdl.handle.net/11468/20450
dc.identifier.volume20en_US
dc.identifier.wosWOS:000409558200004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherKorean Audiological Socen_US
dc.relation.ispartofJournal of Audiology and Otology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTinnitusen_US
dc.subjectParaoxonaseen_US
dc.subjectTotal Oxidant Statusen_US
dc.subjectTotal Antioxidant Statusen_US
dc.subjectOxidative Stress Indexen_US
dc.titleParaoxonase Activity and Oxidative Status in Patients with Tinnitusen_US
dc.titleParaoxonase Activity and Oxidative Status in Patients with Tinnitus
dc.typeArticleen_US

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