Reconstruction techniques in renal injury

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dc.contributor.authorAkay, AF
dc.contributor.authorSahin, H
dc.contributor.authorNergiz, Y
dc.contributor.authorAflay, U
dc.contributor.authorBircan, MK
dc.date.accessioned2024-04-24T17:37:54Z
dc.date.available2024-04-24T17:37:54Z
dc.date.issued2005
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Kidney repair reconstruction techniques are controversial. The conventional technique is suturing, but this is usually with further loss of viable tissue as it promotes scaring. In this animal model, we investigated the parenchymal effect of different sutures and methods. Methods: We carried out this study in the year 2000 in the Animal Laboratory of Dicle University, Diyarbakir, Turkey. We used 40 New Zealand white rabbits in this study, randomized into 5 groups. We separated the left kidney from Gerota's fascia, and performed standard lacerations with incisions 5 mm deep and 10 mm in length. We performed no reconstruction procedure in group 1, and used homeostatic collagen powder in group 2. We primarily sutured the lacerations with chromic gut (4/0) in group 3, and sutured the kidney in group 4 with polyglactin (4/0). We wrapped the kidney with a polyglactin mesh in group 5. We sacrificed 2 rabbits in each group postoperatively on day 2, 15, 45 and 90, and performed left nephrectomy for histological investigation, and assessed interstitial inflammation. Results: While group 5 established the best results, the other 4 groups had similar intermediate results. The pseudocapsule was visible macroscopically in the polyglactin mesh group. We could see mononuclear cell infiltration, dilatation of tubules, atrophy of tubules, and interstitial fibrosis in all groups except group 5. Conclusion: In this animal model, we found that the most appropriate repair material for kidney surgery was polyglactin mesh.en_US
dc.identifier.endpage1754en_US
dc.identifier.issn0379-5284
dc.identifier.issue11en_US
dc.identifier.pmid16311660
dc.identifier.scopus2-s2.0-28844459873
dc.identifier.scopusqualityQ2
dc.identifier.startpage1750en_US
dc.identifier.urihttps://hdl.handle.net/11468/21237
dc.identifier.volume26en_US
dc.identifier.wosWOS:000234097600013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSaudi Med Jen_US
dc.relation.ispartofSaudi Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleReconstruction techniques in renal injuryen_US
dc.titleReconstruction techniques in renal injury
dc.typeArticleen_US

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