Apelin Levels In Isolated Coronary Artery Ectasia

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dc.contributor.authorBilik, Mehmet Zihni
dc.contributor.authorKaplan, Ibrahim
dc.contributor.authorYildiz, Abdulkadir
dc.contributor.authorAkil, Mehmet Ata
dc.contributor.authorAcet, Halit
dc.contributor.authorYuksel, Murat
dc.contributor.authorPolat, Nihat
dc.date.accessioned2024-04-24T17:24:11Z
dc.date.available2024-04-24T17:24:11Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground and Objectives: The etiopathogenesis of coronary artery ectasia (CAE) is not known completely. In most of the cases, CAE is associated with atherosclerosis; however, isolated CAE has a nonatherosclerotic mechanism. The association between atherosclerotic coronary artery disease and apelin has been examined in previous studies. However, the role of plasma apelin in isolated coronary artery ectasia has not been studied. In this study, we investigated the relationship between plasma apelin levels and isolated coronary artery ectasia. Subjects and Methods: The study population included a total of 54 patients. Twenty-six patients had isolated CAE (53.6 +/- 8.1 years); 28 patients with normal coronary arteries (51.6 +/- 8.8 years) and with similar risk factors and demographic characteristics served as the control group. Apelin levels were measured using an enzyme-linked immunoassay kit. Results: Apelin level in the CAE group was significantly lower (apelin=0.181 +/- 0.159 ng/mL) than that in the control group (apelin=0.646 +/- 0.578 ng/mL) (p=0.033). Glucose, creatinine, total cholesterol, triglyceride, low density lipoprotein cholesterol, and high density lipoprotein cholesterol levels were not significantly different between the two groups. Conclusion: In this study, we showed that patients with isolated CAE have decreased plasma apelin levels compared with the control group. Based on the data, a relationship between plasma apelin and isolated CAE was determined.en_US
dc.description.sponsorshipDicle University DUBAPen_US
dc.description.sponsorshipWe are grateful to Dicle University DUBAP for their sponsorship about English editing of this manuscript.en_US
dc.identifier.doi10.4070/kcj.2015.45.5.386
dc.identifier.endpage390en_US
dc.identifier.issn1738-5520
dc.identifier.issn1738-5555
dc.identifier.issue5en_US
dc.identifier.pmid26413106
dc.identifier.scopus2-s2.0-84942304010
dc.identifier.scopusqualityQ2
dc.identifier.startpage386en_US
dc.identifier.urihttps://doi.org/10.4070/kcj.2015.45.5.386
dc.identifier.urihttps://hdl.handle.net/11468/19502
dc.identifier.volume45en_US
dc.identifier.wosWOS:000361970400007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherKorean Soc Cardiologyen_US
dc.relation.ispartofKorean Circulation Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectApelin Proteinen_US
dc.subjectHumanen_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectDilatationen_US
dc.subjectPathologicen_US
dc.subjectInflammationen_US
dc.titleApelin Levels In Isolated Coronary Artery Ectasiaen_US
dc.titleApelin Levels In Isolated Coronary Artery Ectasia
dc.typeArticleen_US

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