The relationship between fibrinogen to albumin ratio and severity of coronary artery disease in patients with STEMI

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dc.contributor.authorKarahan, Oguz
dc.contributor.authorAcet, Halit
dc.contributor.authorErtas, Faruk
dc.contributor.authorTezcan, Orhan
dc.contributor.authorCaliskan, Ahmet
dc.contributor.authorDemir, Muhammed
dc.contributor.authorKaya, Ahmet Ferhat
dc.date.accessioned2024-04-24T16:10:44Z
dc.date.available2024-04-24T16:10:44Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Previous studies show that serum fibrinogen levels are established risk factors for coronary artery disease (CAD) and that serum albumin levels are of a higher specificity and sensitivity in ST-elevation myocardial infarction (STEMI). In this study, we sought to evaluate the association between fibrinogen to albumin ratio (FAR) and the extent and severity of CAD evaluated by TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries (SYNTAX) Score (SS) in patients with STEMI. Methods: A total of 278 patients with STEMI were included in the study. FAR was calculated using specified variables. The extent and severity of CAD were evaluated using the SS. The patients were divided into low( SS < 22) and high- (SS >= 22) risk groups. A Spearman rank correlation coefficient analysis was used for the relationship between FAR and SS. The cutoff points for sensitivity and specificity of FAR in predicting SS were estimated by performing a receiver operator characteristic curve analysis. Results: There were significant differences in the mean age (P = .016), admission serum albumin (P = .041), serum fibrinogen (P < .001), FAR (P < .001), and SS risk groups. Positive correlation was detected between FAR and SS (r = 0.458, P < .001). A cutoff level of >87 FAR predicted SS (sensitivity, 70%; specificity, 70%), and an area under the curve of 0.758 serum fibrinogen and albumin level was an independent predictor for SS in patients with STEMI (b = 0.039; 95% confidence interval, 0.016-0.062; P = .001 and b = -6.906; 95% confidence interval,-12.284 to -1.527; P = .013, respectively). Conclusion: In the present study, we showed that FAR is significantly related to SS in predicting the severity of CAD in patients with STEMI. (C) 2016 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajem.2016.03.003
dc.identifier.endpage1042en_US
dc.identifier.issn0735-6757
dc.identifier.issn1532-8171
dc.identifier.issue6en_US
dc.identifier.pmid27017405
dc.identifier.scopus2-s2.0-84961793695
dc.identifier.scopusqualityQ1
dc.identifier.startpage1037en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajem.2016.03.003
dc.identifier.urihttps://hdl.handle.net/11468/15068
dc.identifier.volume34en_US
dc.identifier.wosWOS:000377338700018
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofAmerican Journal of Emergency Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleThe relationship between fibrinogen to albumin ratio and severity of coronary artery disease in patients with STEMIen_US
dc.titleThe relationship between fibrinogen to albumin ratio and severity of coronary artery disease in patients with STEMI
dc.typeArticleen_US

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