A prospective study of etiology of childhood acute bacterial meningitis, Turkey

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dc.contributor.authorCeyhan, Mehmet
dc.contributor.authorYildirim, Inci
dc.contributor.authorBalmer, Paul
dc.contributor.authorBorrow, Ray
dc.contributor.authorDikici, Bünyamin
dc.contributor.authorTurgut, Mehmet
dc.contributor.authorKurt, Nese
dc.date.accessioned2024-04-24T17:20:40Z
dc.date.available2024-04-24T17:20:40Z
dc.date.issued2008
dc.departmentDicle Üniversitesien_US
dc.description.abstractDetermination of the etiology of bacterial meningitis and estimating cost of disease are important in guiding vaccination policies. To determine the incidence and etiology of meningitis in Turkey, cerebrospinal fluid (CSF) samples were obtained prospectively from children (1 month-17 years of age) with a clinical diagnosis of acute bacterial meningitis. Multiplex PCR was used to detect DNA evidence of Streptococcus pneumoniae, Haemophilus influenzae type b (Hib), and Neisseria meningitidis. In total, 408 CSF samples were collected, and bacterial etiology was determined in 243 cases; N. meningitidis was detected in 56.5%, S. pneumoniae in 22.5%, and Hib in 20.5% of the PCR-positive samples. Among N. meningitidis-positive CSF samples, 42.7%, 31.1%, 2.2%, and 0.7% belonged to serogroups W-135, B, Y, and A, respectively. This study highlights the emergence of serogroup W-135 disease in Turkey and concludes that vaccines to prevent meningococcal disease in this region must provide reliable protection against this serogroup.en_US
dc.identifier.doi10.3201/eid1407.070938
dc.identifier.endpage1096en_US
dc.identifier.issn1080-6040
dc.identifier.issn1080-6059
dc.identifier.issue7en_US
dc.identifier.pmid18598630
dc.identifier.scopus2-s2.0-46349089122
dc.identifier.scopusqualityQ1
dc.identifier.startpage1089en_US
dc.identifier.urihttps://doi.org/10.3201/eid1407.070938
dc.identifier.urihttps://hdl.handle.net/11468/19191
dc.identifier.volume14en_US
dc.identifier.wosWOS:000257294700013
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherCenters Disease Control & Preventionen_US
dc.relation.ispartofEmerging Infectious Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keyword]en_US
dc.titleA prospective study of etiology of childhood acute bacterial meningitis, Turkeyen_US
dc.titleA prospective study of etiology of childhood acute bacterial meningitis, Turkey
dc.typeArticleen_US

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