Comparison of Demodex folliculorum density in haemodialysis patients with a control group

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dc.contributor.authorDuezguen, O. Yagdiran
dc.contributor.authorAytekin, S.
dc.date.accessioned2024-04-24T17:11:35Z
dc.date.available2024-04-24T17:11:35Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground Demodex folliculorum (DF) is resident in human pilosebaceous follicles. Mite density is low in healthy skin. Many cases of demodicosis in association with immunosuppression have been reported. Patients undergoing haemodialysis are also immunosuppressed. Objective We aimed to compare the Demodex folliculorum density in haemodialysis patients and healthy subjects. Methods Mite density of 87 patients undergoing haemodialysis was compared with that of age- and sex-matched controls. Two samples of standardized skin surface biopsies were taken from each subject from the forehead, cheek and nose. The number of mites counted on the surface area of 1 cm(2) was accepted as the density of DF. The length and width of mites were measured by oculometer. Results DF density was found in 17 (19.54%) of the 87 dialysis patients and in 9 (10.34%) of 87 controls. A mean mite density of 5.11 +/- 5.65 was found in dialysis patients and of 2.55 +/- 1.6 in controls. Differences between the two groups in mite density were not statistically significant (P = 0.13). There was also no significant difference in mite length between the two groups (P = 0.06). There was, however, a significant difference in mite width (P = 0.018). Conclusion Despite the presence of sebaceous gland atrophy in haemodialysis patients, the higher density of DF in these patients than controls supports the supposition that this mite can increase immunosuppression.en_US
dc.identifier.doi10.1111/j.1468-3083.2006.01926.x
dc.identifier.endpage483en_US
dc.identifier.issn0926-9959
dc.identifier.issue4en_US
dc.identifier.pmid17373974
dc.identifier.scopus2-s2.0-33947409022
dc.identifier.scopusqualityQ1
dc.identifier.startpage480en_US
dc.identifier.urihttps://doi.org/10.1111/j.1468-3083.2006.01926.x
dc.identifier.urihttps://hdl.handle.net/11468/17621
dc.identifier.volume21en_US
dc.identifier.wosWOS:000244968900007
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherBlackwell Publishingen_US
dc.relation.ispartofJournal of The European Academy of Dermatology and Venereology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDemodexen_US
dc.subjectHaemodialysisen_US
dc.subjectImmunosuppressionen_US
dc.subjectUraemiaen_US
dc.titleComparison of Demodex folliculorum density in haemodialysis patients with a control groupen_US
dc.titleComparison of Demodex folliculorum density in haemodialysis patients with a control group
dc.typeArticleen_US

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