Prescribing pattern of antihypertensive drugs in primary care units in Turkey: results from the TURKSAHA study

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dc.contributor.authorAbaci, Adnan
dc.contributor.authorKozan, Omer
dc.contributor.authorOguz, Aytekin
dc.contributor.authorSahin, Mahmut
dc.contributor.authorDeger, Necmi
dc.contributor.authorSenocak, Huseyin
dc.contributor.authorToprak, Nizamettin
dc.date.accessioned2024-04-24T15:59:49Z
dc.date.available2024-04-24T15:59:49Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective The prescribing pattern of drugs used for treating hypertension changes over time in response to changes in recommended guidelines and innovations in drug formulations, among others. In addition, the classes of antihypertensive drugs used vary among the countries. The aim of this study was to investigate the practice of antihypertensive medications in primary care units in Turkey. Methods TURKSAHA is a cross-sectional screening study conducted in 1000 primary care units considered to be representative of primary care in Turkey, with the purpose of defining the demographic characteristics, clinical features, rate of blood pressure control achieved and the antihypertensive drugs prescribed for the hypertensive patients treated in these centers. In this analysis, we investigated the agents used in the treatment regimen. Results Of the 16,270 patients considered to be eligible for inclusion in the study, 15,187 (93.3%) were on an antihypertensive treatment, and 1083 (6.7%) were receiving no treatment. Patients who received treatment but whose antihypertensive medication was not specified (2290 patients) were subsequently excluded, and the trial was carried out with the remaining 12,897 patients. The mean age of the patients was 60 +/- 11 years (60.2% female). Of the 12,897 patients, 75.7% were receiving monotherapy, 19.7% two drugs, 4.1% three drugs and 0.5% four or more drugs. The rate of successful blood pressure control (< 140/90 mmHg; for diabetics < 130/80 mm Hg) in relation to the number of drugs received was 26.3, 25.9, 24.5 and 26.2%, respectively. Among the patients receiving monotherapy, the most frequently used antihypertensive drug class was angiotensin-converting enzyme inhibitors (30.1%), followed by beta-blockers (20.6%), calcium-channel blockers (17.9%), diuretics (15.4%) and angiotensin-receptor blockers (14%). Conclusion As in other European countries, the rate of successful blood pressure control was low among hypertensive patients receiving treatment, and despite the inadequacy of monotherapy to control blood pressure, many of the patients continued this treatment regimen. Consistent with the global trend, the most frequently prescribed anti-hypertensives were angiotensin blockers.en_US
dc.identifier.doi10.1007/s00228-007-0266-8
dc.identifier.endpage402en_US
dc.identifier.issn0031-6970
dc.identifier.issn1432-1041
dc.identifier.issue4en_US
dc.identifier.pmid17279356
dc.identifier.scopus2-s2.0-33947130152
dc.identifier.scopusqualityQ2
dc.identifier.startpage397en_US
dc.identifier.urihttps://doi.org/10.1007/s00228-007-0266-8
dc.identifier.urihttps://hdl.handle.net/11468/14269
dc.identifier.volume63en_US
dc.identifier.wosWOS:000244821400009
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofEuropean Journal of Clinical Pharmacology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAngiotensin Blockersen_US
dc.subjectAntihypertensive Medicationen_US
dc.subjectTurksaha Studyen_US
dc.titlePrescribing pattern of antihypertensive drugs in primary care units in Turkey: results from the TURKSAHA studyen_US
dc.titlePrescribing pattern of antihypertensive drugs in primary care units in Turkey: results from the TURKSAHA study
dc.typeArticleen_US

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