The Ratio of Fibrinogen to Albumin as a Predictor of Contrast-Induced Nephropathy After Carotid Angiography

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dc.contributor.authorErtas, Faruk
dc.contributor.authorAvci, Eyup
dc.contributor.authorKiris, Tuncay
dc.date.accessioned2024-04-24T17:14:32Z
dc.date.available2024-04-24T17:14:32Z
dc.date.issued2019
dc.departmentDicle Üniversitesien_US
dc.description.abstractContrast-induced nephropathy (CIN) is acute kidney failure that occurs after exposure to contrast agent. There is no sensitive biomarker to predict the development of CIN. In a retrospective study, we investigated the predictive value of the fibrinogen to albumin ratio (FAR) to determine the risk of CIN in patients (N = 246) who underwent carotid angiography. Contrast-induced nephropathy was defined as a 0.5 mg/dL or 25% increase in serum creatinine levels 48 to 72 hours following exposure to a radiocontrast agent. Patients were grouped according to whether they developed CIN or not, that is, CIN(-) and CIN(+) groups, respectively. Contrast-induced nephropathy developed in 39 (15.8%) of all the patients. The fibrinogen levels, neutrophil to lymphocyte ratio (NLR), and FAR in the CIN (+) group were higher than in the CIN (-) group (P < .001). Multivariate analysis showed that age, diabetes, NLR, platelet-lymphocyte ratio, and FAR were independent risk factors for CIN. The area under the curve (AUC) of FAR was 0.800 for the prediction of CIN, and the best cutoff value was 57.4 with sensitivity, specificity, positive predictive value, and negative predictive value of 74.4%, 60.8%, 26.4%, and 92.7%, respectively. The FAR may be useful as a predictor of CIN.en_US
dc.identifier.doi10.1177/0003319718809200
dc.identifier.endpage464en_US
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue5en_US
dc.identifier.pmid30373374
dc.identifier.scopus2-s2.0-85059910427
dc.identifier.scopusqualityQ2
dc.identifier.startpage458en_US
dc.identifier.urihttps://doi.org/10.1177/0003319718809200
dc.identifier.urihttps://hdl.handle.net/11468/18033
dc.identifier.volume70en_US
dc.identifier.wosWOS:000463230500010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCarotid Angiographyen_US
dc.subjectContrast-Induced Nephropathyen_US
dc.subjectFibrinogen To Albumin Ratioen_US
dc.titleThe Ratio of Fibrinogen to Albumin as a Predictor of Contrast-Induced Nephropathy After Carotid Angiographyen_US
dc.titleThe Ratio of Fibrinogen to Albumin as a Predictor of Contrast-Induced Nephropathy After Carotid Angiography
dc.typeArticleen_US

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