A Focused review on cognitive improvement by the genus Salvia L. (Sage)-from ethnopharmacology to clinical evidence

dc.contributor.authorErtas, Abdulselam
dc.contributor.authorYigitkan, Serkan
dc.contributor.authorOrhan, Ilkay Erdogan
dc.date.accessioned2024-04-24T17:20:53Z
dc.date.available2024-04-24T17:20:53Z
dc.date.issued2023
dc.departmentDicle Üniversitesien_US
dc.description.abstractEthnopharmacology has been an important starting point in medical and pharmaceutical sciences for discovering drug candidates from natural sources. In this regard, the genus Salvia L., commonly known as sage, is one of the best-known medicinal and aromatic plants of the Lamiaceae family; it has been recorded as being used for memory enhancement in European folk medicine. Despite the various uses of sage in folk medicines, the records that have pointed out sage's memory-enhancing properties have paved the way for the aforementioned effect to be proven on scientific grounds. There are many preclinical studies and excellent reviews referring to the favorable effect of different species of sage against the cognitive dysfunction that is related to Alzheimer's disease (AD). Hence, the current review discusses clinical studies that provide evidence for the effect of Salvia species on cognitive dysfunction. Clinical studies have shown that some Salvia species, i.e., hydroalcoholic extracts and essential oils of S. officinalis L. and S. lavandulaefolia leaves in particular, have been the most prominently effective species in patients with mild to moderate AD, and these species have shown positive effects on the memory of young and healthy people. However, the numbers of subjects in the studies were small, and standardized extracts were not used for the most part. Our review points out to the need for longer-term clinical studies with higher numbers of subjects being administered standardized sage preparations.en_US
dc.identifier.citationErtaş, A., Yiğitkan, S. ve Orhan, İ. E. (2023). A focused review on cognitive improvement by the Genus Salvia L. (Sage)—from ethnopharmacology to clinical evidence. Pharmaceuticals, 16(2), 1-18.
dc.identifier.doi10.3390/ph16020171
dc.identifier.issn1424-8247
dc.identifier.issue2en_US
dc.identifier.pmid37259321
dc.identifier.scopus2-s2.0-85148647529
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.3390/ph16020171
dc.identifier.urihttps://hdl.handle.net/11468/19285
dc.identifier.volume16en_US
dc.identifier.wosWOS:000940810100001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofPharmaceuticals
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSalviaen_US
dc.subjectSageen_US
dc.subjectMemory enhancementen_US
dc.subjectEthnopharmacologyen_US
dc.subjectClinical studyen_US
dc.subjectAlzheimer's diseaseen_US
dc.subjectCognitive dysfunctionen_US
dc.titleA Focused review on cognitive improvement by the genus Salvia L. (Sage)-from ethnopharmacology to clinical evidenceen_US
dc.titleA Focused review on cognitive improvement by the genus Salvia L. (Sage)-from ethnopharmacology to clinical evidence
dc.typeReview Articleen_US

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