Reliability of frozen section examination of external iliac, hypogastric, and obturator lymph nodes during radial cystectomy

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dc.contributor.authorAdsan, Oztug
dc.contributor.authorBaltaci, Sumer
dc.contributor.authorCal, Cag
dc.contributor.authorBuyukalpelli, Recep
dc.contributor.authorUgurlu, Ogurlu
dc.contributor.authorBozlu, Murat
dc.contributor.authorTurkolmez, Kadir
dc.date.accessioned2024-04-24T16:18:34Z
dc.date.available2024-04-24T16:18:34Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVES To evaluate the accuracy of frozen section examination (FSE) for detecting lymph node (LN) metastasis in patients with bladder cancer undergoing radical cystectomy and pelvic LN dissection. To our knowledge, the accuracy of FSE to identify LN metastases in patients with bladder cancer is still undetermined. METHODS The clinical data of 360 patients who had undergone radical cystectomy with pelvic lymphadenectomy for bladder cancer in six urologic institutions were retrospectively analyzed. The nodal regions included were the external iliac, hypogastric, and obturator LNs. The FSE results of the right and left LN regions were compared with the final histopathologic results of the respective LN regions. RESULTS The final pathologic examination revealed nodal metastases in 65 patients (18.1%). Of the 720 right and left LN regions in 360 patients, 88 (12.2%) were metastatic at the final pathologic examination. Although the FSE findings were negative, the final pathologic examination revealed LN metastases in 26 patients and in 29 pelvic LN regions. All LN. regions with positive FSE findings were positive at the final pathologic examination. When we considered the 720 LN regions, the sensitivity, specificity, and positive and negative predictive values for FSE were 67%, 100%, 100%, and 95.6%, respectively. CONCLUSIONS Until innovations in imaging methods improve nodal staging in patients with bladder cancer, performing FSE of the external iliac, hypogastric, and obturator LNs seems to be a reliable procedure for the evaluation of the LNs. The information obtained with FSE of the LNs can be used to determine intraoperatively the extent of LN dissection. (c) 2007 Elsevier Inc.en_US
dc.identifier.doi10.1016/j.urology.2006.09.042
dc.identifier.endpage86en_US
dc.identifier.issn0090-4295
dc.identifier.issue1en_US
dc.identifier.pmid17270622
dc.identifier.scopus2-s2.0-33846527272
dc.identifier.scopusqualityQ2
dc.identifier.startpage83en_US
dc.identifier.urihttps://doi.org/10.1016/j.urology.2006.09.042
dc.identifier.urihttps://hdl.handle.net/11468/16173
dc.identifier.volume69en_US
dc.identifier.wosWOS:000244114600026
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofUrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleReliability of frozen section examination of external iliac, hypogastric, and obturator lymph nodes during radial cystectomyen_US
dc.titleReliability of frozen section examination of external iliac, hypogastric, and obturator lymph nodes during radial cystectomy
dc.typeArticleen_US

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