Nutritional megaloblastic anemia in young Turkish children is associated with vitamin B-12 deficiency and psychomotor retardation

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dc.contributor.authorKatar, Selahattin
dc.contributor.authorOzbek, Mehmet Nuri
dc.contributor.authorYaramis, Ahmet
dc.contributor.authorEcer, Sultan
dc.date.accessioned2024-04-24T17:08:12Z
dc.date.available2024-04-24T17:08:12Z
dc.date.issued2006
dc.departmentDicle Üniversitesien_US
dc.description.abstractWe aimed to investigate the presence of psychomotor retardation, physical and laboratory examination in infants with megaloblastic anemia. Inclusion criteria for the study were; age 9 to 36 months, refusal of food except for breast and cow milk, loss of appetite, developmental delay, significant pallor, and hypersegmentation neutrophils in the peripheral blood smear. A total of 33 children fulfilling the inclusion criteria were enrolled among 3368 patients attending Pediatric Outpatient Clinics of Sirnak-Cizre State Hospital between January 25, 2004 and May 5, 2004. Mean age was 16.4 months. Thirty-two patients had Vitamin B(12) deficiency, 1 patient had folate deficiency, and 10 patients had combined vitamin B(12) and folate deficiency. Statistically, a positive significant relationship was detected between serum vitamin B(12) levels and mean corpuscular volume (P = 0.001, r = 0.56), and between vitamin B(12) levels and hemoglobin (P = 0.004, r = 0.49). We believe that preventative measures such as fortification of flour with vitamin B(12), nutritional support with vitamin B(12) for the mother during pregnancy and nursing, provision of adequate primary preventive health services, and starting complementary food after 6 months of age are important determinants for preventing megaloblastic anemia.en_US
dc.identifier.doi10.1097/01.mph.0000212958.89091.c0
dc.identifier.endpage562en_US
dc.identifier.issn1077-4114
dc.identifier.issue9en_US
dc.identifier.pmid17006260
dc.identifier.scopus2-s2.0-33749335286
dc.identifier.scopusqualityQ3
dc.identifier.startpage559en_US
dc.identifier.urihttps://doi.org/10.1097/01.mph.0000212958.89091.c0
dc.identifier.urihttps://hdl.handle.net/11468/17251
dc.identifier.volume28en_US
dc.identifier.wosWOS:000241311500003
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal of Pediatric Hematology Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChilden_US
dc.subjectNutritional Vitamin B(12) And Folate Deficiencyen_US
dc.subjectPsychomotor Retardationen_US
dc.titleNutritional megaloblastic anemia in young Turkish children is associated with vitamin B-12 deficiency and psychomotor retardationen_US
dc.titleNutritional megaloblastic anemia in young Turkish children is associated with vitamin B-12 deficiency and psychomotor retardation
dc.typeArticleen_US

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