Cranial magnetic resonance imaging findings of nutritional Vitamin B12 deficiency in 15 hypotonic infants

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dc.contributor.authorTaskesen, Mustafa
dc.contributor.authorYaramis, Ahmet
dc.contributor.authorPirinccioglu, Ayfer Gozu
dc.contributor.authorEkici, Faysal
dc.date.accessioned2024-04-24T16:11:21Z
dc.date.available2024-04-24T16:11:21Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Nutritional vitamin B-12 deficieny is common among infants in the developing and underdeveloped countries. There is limited information concerning neuroimaging findings in infants with vitamin B-12 deficiency in the literature. Aims: The aim of this study is to evaluate the cranial magnetic resonance imaging (MRI) changes and clinical characteristics of hypotonic infants due to vitamin B-12 deficiency. Materials and methods: A total of 15 infants with neuroradiologic investigations were diagnosed with nutritional B-12 vitamin deficiency. Cranial MRI was performed on all infants. Results: Five infants were female (33%) and the mean age of infants was 12.3 +/- 5.5 months. Hypotonia and neurodevelopmental retardation were present in all patients. MRI demonstrated thinning of the corpus callosum in 6 (40%), cortical atrophy in 5 (33.3%), large sylvian fissures in 5 (33.3%), ventricular dilatation in 3 (20%), asymetric large lateral ventricle in 2 (13.3%) and delayed in myelination in 2(13.3%) patients. Four infants had normal MRI findings. Conclusion: Because of the importance of vitamin B-12 in the development of the brain, MRI findings may be detected and useful in infants with vitamin B-12 deficiency. (C) 2011 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ejpn.2011.08.005
dc.identifier.endpage270en_US
dc.identifier.issn1090-3798
dc.identifier.issue3en_US
dc.identifier.pmid21903432
dc.identifier.scopus2-s2.0-84859969604
dc.identifier.scopusqualityQ1
dc.identifier.startpage266en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejpn.2011.08.005
dc.identifier.urihttps://hdl.handle.net/11468/15361
dc.identifier.volume16en_US
dc.identifier.wosWOS:000303695400007
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofEuropean Journal of Paediatric Neurology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCranial Magnetic Resonance Imagingen_US
dc.subjectVitamin B-12 Deficiencyen_US
dc.subjectHypotoniaen_US
dc.subjectInfanten_US
dc.titleCranial magnetic resonance imaging findings of nutritional Vitamin B12 deficiency in 15 hypotonic infantsen_US
dc.titleCranial magnetic resonance imaging findings of nutritional Vitamin B12 deficiency in 15 hypotonic infants
dc.typeArticleen_US

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