The Effect of Aortic Angulation on Clinical Outcomes of Patients Undergoing Transcatheter Aortic Valve Replacement

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dc.contributor.authorAktan, Adem
dc.contributor.authorDemir, Muhammed
dc.contributor.authorGuzel, Tuncay
dc.contributor.authorKarahan, Mehmet Zulkuf
dc.contributor.authorAslan, Burhan
dc.contributor.authorKilic, Raif
dc.contributor.authorGunlu, Serhat
dc.date.accessioned2024-04-24T17:18:30Z
dc.date.available2024-04-24T17:18:30Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction: The aim of this study was to assess the impact of aortic angulation (AA) on periprocedural and in -hospital complications as well as mortality of patients undergoing Evolut (TM) R valve implantation. Methods: A retrospective study was conducted on 264 patients who underwent transfemoral-approach transcatheter aortic valve replacement with self-expandable valve at our hospital between August 2015 and August 2022. These patients underwent multislice computer tomography scans to evaluate AA. Transcatheter aortic valve replacement endpoints, device success, and clinical events were assessed according to the definitions provided by the Valve Academic Research Consortium -3. Cumulative events included paravalvular leak, permanent pacemaker implantation, new-onset stroke, and in -hospital mortality. Patients were divided into two groups, AA <= 48(degrees) and AA > 48(degrees), based on the mean AA measurement (48.3 +/- 8.8) on multislice computer tomography. Results: Multivariable logistic regression analysis was performed to identify predictors of cumulative events, utilizing variables with a P-value < 0.2 obtained from univariable logistic regression analysis, including AA, age, hypertension, chronic renal failure, and heart failure. AA (odds ratio [OR]: 1.73, 95% confidence interval [CI]: 0.89-3.38, P=0.104), age (OR: 1.04, 95% CI: 0.99-1.10, P=0.099), hypertension (OR: 1.66, 95% CI: 0.82-3.33, P=0.155), chronic renal failure (OR: 1.82, 95% CI: 0.92-3.61, P=0.084), and heart failure (OR: 0.57, 95% CI: 0.27-1.21, P=0.145) were not found to be significantly associated with cumulative events in the multivariable logistic regression analysis. Conclusion: This study demonstrated that increased AA does not have a significant impact on intraprocedural and periprocedural complications of patients with new generation self-expandable valves implanted.en_US
dc.identifier.doi10.21470/1678-9741-2022-0436
dc.identifier.issn0102-7638
dc.identifier.issn1678-9741
dc.identifier.issue2en_US
dc.identifier.pmid38426701
dc.identifier.scopus2-s2.0-85186311284
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.21470/1678-9741-2022-0436
dc.identifier.urihttps://hdl.handle.net/11468/18803
dc.identifier.volume39en_US
dc.identifier.wosWOS:001178697200002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSoc Brasil Cirurgia Cardiovascen_US
dc.relation.ispartofBrazilian Journal of Cardiovascular Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAortic Angulationen_US
dc.subjectAortic Stenosisen_US
dc.subjectTranscatheter Aortic Valve Replacementen_US
dc.subjectLogistic Modelsen_US
dc.titleThe Effect of Aortic Angulation on Clinical Outcomes of Patients Undergoing Transcatheter Aortic Valve Replacementen_US
dc.titleThe Effect of Aortic Angulation on Clinical Outcomes of Patients Undergoing Transcatheter Aortic Valve Replacement
dc.typeArticleen_US

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