The Reliability of Fine-Needle Aspiration Biopsy in Terms of Malignancy in Patients With Hashimoto Thyroiditis

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dc.contributor.authorKapan, Murat
dc.contributor.authorOnder, Akin
dc.contributor.authorGirgin, Sadullah
dc.contributor.authorUlger, Burak Veli
dc.contributor.authorFirat, Ugur
dc.contributor.authorUslukaya, Omer
dc.contributor.authorOguz, Abdullah
dc.date.accessioned2024-04-24T17:33:08Z
dc.date.available2024-04-24T17:33:08Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of this study was to analyze the presence of malignancy in patients with Hashimoto's thyroiditis and to investigate the reliability of preoperative fine-needle aspiration biopsy (FNAB). The retrospective study included 44 patients who were operated on for nodular goiter between December 2010 and October 2011. The patients underwent thyroidectomy following a cytologic analysis plus FNAB. Hashimoto's thyroiditis was confirmed on histopathology in all patients. FNAB results were defined as benign in 14 (31.8%), suspicion for malignancy in 17 (38.6%), malignant in 9 (20.5%), and inadequate in 4 (9.1%). Following the thyroidectomy, presence of papillary thyroid carcinoma and follicular variant of papillary thyroid carcinoma were detected in 10 patients (22.7%) and 1 (2.3%) patient, respectively. The FNAB results were interpreted in terms of malignancy, which revealed the sensitivity as 80%; specificity, 40%; false positives, 69.2%; false negatives, 14.3%; positive predictive value, 31.8%; negative predictive value, 85.7%; and diagnostic accuracy, 50%. The coexistence of Hashimoto's thyroiditis with papillary thyroid carcinoma is quite common. The FNAB results for such cases are hard to evaluate, and they are likely to increase the number of false positives.en_US
dc.identifier.doi10.9738/INTSURG-D-13-00209.1
dc.identifier.endpage253en_US
dc.identifier.issn0020-8868
dc.identifier.issue2en_US
dc.identifier.pmid25692426
dc.identifier.scopus2-s2.0-84974529221
dc.identifier.scopusqualityQ4
dc.identifier.startpage249en_US
dc.identifier.urihttps://doi.org/10.9738/INTSURG-D-13-00209.1
dc.identifier.urihttps://hdl.handle.net/11468/20463
dc.identifier.volume100en_US
dc.identifier.wosWOS:000349957000011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherInt College Of Surgeonsen_US
dc.relation.ispartofInternational Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHashimoto's Thyroiditisen_US
dc.subjectPapillary Thyroid Carcinomaen_US
dc.subjectFine Needle Aspiration Biopsyen_US
dc.titleThe Reliability of Fine-Needle Aspiration Biopsy in Terms of Malignancy in Patients With Hashimoto Thyroiditisen_US
dc.titleThe Reliability of Fine-Needle Aspiration Biopsy in Terms of Malignancy in Patients With Hashimoto Thyroiditis
dc.typeArticleen_US

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