Primary spindle cell sarcoma of the breast

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dc.authorid0000-0002-7168-1507en_US
dc.authorid0000-0002-7451-2786en_US
dc.contributor.authorÇil, Timuçin
dc.contributor.authorAltıntaş, Abdullah
dc.contributor.authorPaşa, Semir
dc.contributor.authorBüyükbayram, Hüseyin
dc.contributor.authorIşıkdoğan, Abdurrahman
dc.date.accessioned2024-04-05T11:43:01Z
dc.date.available2024-04-05T11:43:01Z
dc.date.issued2008en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıklar Ana Bilim Dalıen_US
dc.description.abstractBackground: Primary pure breast sarcoma is a rare disease and constitutes 0.2-1.0% of all mammary malignancies. The establishment of a diagnosis of soft tissue sarcoma is difficult in adults. Immunohistochemical analysis usually proves to be helpful in indistinguishable cases. The simplistic step is to classify sarcomas on a simple descriptive basis as spindle cell sarcomas, myxoid sarcomas, pleomorphic sarcomas, and small round cell sarcomas. Case Report: Here, we present a rare case of primary spindle cell sarcoma of the breast. A 43-year-old woman was admitted to our clinic with a 2-month history of a left breast lump. Histopathological examination showed a tumor of 2.5 cm in diameter and of nuclear and histological grade 2. In the immunohistochemical examination, vimentin positivity, high nuclear overexpression of P53, high Ki-67 and S-100, desmin, leukocyte common antigen, keratin, and smooth muscle antigen, CD34, HMB45 and EMA negativity were detected. Conclusion: Most invasive breast neoplasms are epithelial tumors, and mesenchymal breast tumors are rarely seen. In primary breast sarcoma, adequate surgical tumor excision, tumor grade, and tumor diameter seem to be the most important prognostic factors.en_US
dc.identifier.citationÇil, T., Altıntaş, A., Paşa, S., Büyükbayram, H. ve Işıkdoğan, A. (2008). Primary spindle cell sarcoma of the breast. Breast Care, 3(3), 197-199.en_US
dc.identifier.doi10.1159/000121469
dc.identifier.endpage199en_US
dc.identifier.issn1661-3805
dc.identifier.issue3en_US
dc.identifier.pmid20824039
dc.identifier.scopus2-s2.0-46849091419
dc.identifier.scopusqualityQ1
dc.identifier.startpage197en_US
dc.identifier.urihttps://karger.com/brc/article-pdf/3/3/197/2299523/000121469.pdf
dc.identifier.urihttps://hdl.handle.net/11468/13856
dc.identifier.volume3en_US
dc.identifier.wosWOS:000257423600007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇil, Timuçin
dc.institutionauthorAltıntaş, Abdullah
dc.institutionauthorPaşa, Semir
dc.institutionauthorBüyükbayram, Hüseyin
dc.institutionauthorIşıkdoğan, Abdurrahman
dc.language.isoenen_US
dc.relation.ispartofBreast Care
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast sarcomaen_US
dc.subjectPrimaryen_US
dc.subjectBreast tumoren_US
dc.subjectSpindle cell sarcomaen_US
dc.titlePrimary spindle cell sarcoma of the breasten_US
dc.titlePrimary spindle cell sarcoma of the breast
dc.typeArticleen_US

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