Acoustic Radiation Force Impulse Imaging for Evaluation of Renal Parenchyma Elasticity in Diabetic Nephropathy

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dc.contributor.authorGoya, Cemil
dc.contributor.authorKilinc, Faruk
dc.contributor.authorHamidi, Cihad
dc.contributor.authorYavuz, Alpaslan
dc.contributor.authorYildirim, Yasar
dc.contributor.authorCetincakmak, Mehmet Guli
dc.contributor.authorHattapoglu, Salih
dc.date.accessioned2024-04-24T17:18:39Z
dc.date.available2024-04-24T17:18:39Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVE. The goal of this study is to evaluate the changes in the elasticity of the renal parenchyma in diabetic nephropathy using acoustic radiation force impulse imaging. SUBJECTS AND METHODS. The study included 281 healthy volunteers and 114 patients with diabetic nephropathy. In healthy volunteers, the kidney elasticity was assessed quantitatively by measuring the shear-wave velocity using acoustic radiation force impulse imaging based on age, body mass index, and sex. The changes in the renal elasticity were compared between the different stages of diabetic nephropathy and the healthy control group. RESULTS. In healthy volunteers, there was a statistically significant correlation between the shear-wave velocity values and age and sex. The shear-wave velocity values for the kidneys were 2.87, 3.14, 2.95, 2.68, and 2.55 m/s in patients with stage 1, 2, 3, 4, and 5 diabetic nephropathy, respectively, compared with 2.35 m/s for healthy control subjects. Acoustic radiation force impulse imaging was able to distinguish between the different diabetic nephropathy stages (except for stage 5) in the kidneys. The threshold value for predicting diabetic nephropathy was 2.43 m/s (sensitivity, 84.1%; specificity, 67.3%; positive predictive value, 93.1%; negative predictive value 50.8%; accuracy, 72.1%; positive likelihood ratio, 2.5; and negative likelihood ratio, 0.23). CONCLUSION. Acoustic radiation force impulse imaging could be used for the evaluation of the renal elasticity changes that are due to secondary structural and functional changes in diabetic nephropathy.en_US
dc.identifier.doi10.2214/AJR.14.12493
dc.identifier.endpage329en_US
dc.identifier.issn0361-803X
dc.identifier.issn1546-3141
dc.identifier.issue2en_US
dc.identifier.pmid25615754
dc.identifier.scopus2-s2.0-84928530475
dc.identifier.scopusqualityQ1
dc.identifier.startpage324en_US
dc.identifier.urihttps://doi.org/10.2214/AJR.14.12493
dc.identifier.urihttps://hdl.handle.net/11468/18862
dc.identifier.volume204en_US
dc.identifier.wosWOS:000348652300036
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherAmer Roentgen Ray Socen_US
dc.relation.ispartofAmerican Journal of Roentgenology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiabetic Nephropathyen_US
dc.subjectElastographyen_US
dc.subjectEnd-Stage Renal Diseaseen_US
dc.titleAcoustic Radiation Force Impulse Imaging for Evaluation of Renal Parenchyma Elasticity in Diabetic Nephropathyen_US
dc.titleAcoustic Radiation Force Impulse Imaging for Evaluation of Renal Parenchyma Elasticity in Diabetic Nephropathy
dc.typeArticleen_US

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