Can direct bilirubin-to-lymphocyte ratio predict surgery for pediatric adhesive small bowel obstruction?

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dc.contributor.authorAzizoglu, Mustafa
dc.contributor.authorArslan, Serkan
dc.contributor.authorKamci, Tahsin O.
dc.contributor.authorBasuguy, Erol
dc.contributor.authorAydogdu, Bahattin
dc.contributor.authorKarabel, Muesemma A.
dc.contributor.authorOkur, Mehmet H.
dc.date.accessioned2025-02-22T14:08:43Z
dc.date.available2025-02-22T14:08:43Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Estimating which patients might require surgical intervention is crucial. Patients with complete bowel obstructions exhibit disrupted enterohepatic cycles of bile and bacteremia due to bacterial translocation. The goal of this study was to develop a prediction index using laboratory inflammatorydatato identifypatients who mayneed surgery. Materials and methods: The patients were divided into two groups based on their management strategy: Non -operative management (Group 1) and surgical management (Group 2). Results: The indirect bilirubin, direct bilirubin, and total bilirubin were significantly higher in Group 2 than in Group 1 (p = 0.001, p < 0.001, and p < 0.001, respectively). The neutrophil-to-lymphocyte ratio (NLR), platelet-to-NLR (PNLR), and direct bilirubin-to-lymphocyte ratio (DBR) were significantly higher in Group 2 compared to Group 1 (p = 0.041, p = 0.020, and p < 0.001, respectively). In group 2, 78% have viable bowels. Resection was performed in 40% of cases, with 12% mortality and a 10 -day average hospital stay. DLR performs the best overall accuracy (72%), demonstrating a well-balanced sensitivity (62%) and specificity (81%). Conclusions: This study suggested that DBR is a more accurate predictive index for surgical intervention in pediatric adhesive small bowel obstruction patients compared to NLR and PNLR, providing valuable guidance for treatment strategies.en_US
dc.identifier.doi10.24875/CIRU.23000524
dc.identifier.issn0009-7411
dc.identifier.issue3en_US
dc.identifier.pmid38862103en_US
dc.identifier.scopus2-s2.0-85195888288en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.24875/CIRU.23000524
dc.identifier.urihttps://hdl.handle.net/11468/29596
dc.identifier.volume92en_US
dc.identifier.wosWOS:001244811100003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isospen_US
dc.publisherMexican Acad Surgeryen_US
dc.relation.ispartofCirugia Y Cirujanosen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectNeutrophil-to-lymphocyte ratio.en_US
dc.subjectPlatelet-to-neutrophil-to-lymphocyte ratioen_US
dc.subjectDirect bilirubin-to-lymphocyte ratioen_US
dc.subjectAdhesive small bowel obstructionen_US
dc.titleCan direct bilirubin-to-lymphocyte ratio predict surgery for pediatric adhesive small bowel obstruction?en_US
dc.typeArticleen_US

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