Synthesis and reactions of new 2-hydroxymethyldimethoxyindoles
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Tarih
2016
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pergamon-Elsevier Science Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Lithium aluminium hyride was used as a reducing agent to prepare a range of 2-hydroxymethyldimethoxyindole derivatives from the related methyl esters. Acid-catalysed reactions of these indole-2-methanols yielded indolo-cyclotriveratrylenes linked through C-2 and C-3. The related indole-2-carbaldehydes were prepared via oxidation of the indole-2-methanols in the presence of manganese dioxide. Vilsmeier formylation was explored to prepare new formylated indole-2-carbaldehydes. Furthermore, the treatment of indole-2-carbaldehydes with nitromethane led to the formation of 2-nitrovinylindoles. (C) 2015 Elsevier Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
2-Hydroxydimethoxyindoles, Reduction, Oxidation, Indolo-Cyclotriveratrylene, 2-Nitrovinylindole
Kaynak
Tetrahedron
WoS Q Değeri
Q2
Scopus Q Değeri
Q3
Cilt
72
Sayı
1
