The effect of biological agent treatment on neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, mean platelet volume, and C-reactive protein in psoriasis patients

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dc.authorid0000-0003-0675-5204en_US
dc.contributor.authorAn, İsa
dc.contributor.authorUçmak, Derya
dc.date.accessioned2021-08-17T05:57:18Z
dc.date.available2021-08-17T05:57:18Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Deri ve Zührevi Hastalıklar Ana Bilim Dalıen_US
dc.description.abstractIntroduction: In recent years, the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), mean platelet volume (MPV) and C reactive protein (CRP) have been shown to be important indicators of systemic inflammation. Studies have shown that NLR, PLR, MPV and CRP are higher in psoriasis patients than in the control group. Aim: To investigate the NLR, PLR, MPV and serum CRP levels in patients who were treated with biological agents for psoriasis. Material and methods: In our study, 75 patients who were followed up and had a diagnosis of psoriasis vulgaris and took a biological agent therapy between January 2014 and December 2017 in the Dermatology Clinic of the Dicle University Medical Faculty Hospital were evaluated before treatment, and 3 and 6 months after treatment. Results: Neutrophil count, lymphocyte count, thrombocyte count, NLR, PLR, MPV and CRP values before the biological agent treatment were statistically higher than the values at 3 and 6 months of treatment. There was no statistically significant difference between pre-treatment neutrophil, lymphocyte, leukocyte, platelet, NLR, PLR, MPV, CRP values and values at 3 and 6 months after treatment when we compared four different biological agents. Conclusions: It was seen that NLR, PLR, MPV and CRP values decreased independently of the type of the biological agent used in our study. Therefore, we think that these parameters can be used to evaluate the effects of biological agent treatment on systemic inflammation in psoriasis patients and to monitor the course of the disease.en_US
dc.identifier.citationAn, İ. ve Uçmak, D. (2020). The effect of biological agent treatment on neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, mean platelet volume, and C-reactive protein in psoriasis patients. Postepy Dermatologii i Alergologii, 37(2), 202-206.en_US
dc.identifier.doi10.5114/ada.2020.94838
dc.identifier.endpage206en_US
dc.identifier.issn1642-395X
dc.identifier.issue2en_US
dc.identifier.pmid32489355
dc.identifier.scopus2-s2.0-85086847005
dc.identifier.scopusqualityQ2
dc.identifier.startpage202en_US
dc.identifier.urihttps://www.termedia.pl/The-effect-of-biological-agent-treatment-on-neutrophil-to-lymphocyte-ratio-platelet-to-lymphocyte-ratio-mean-platelet-volume-and-C-reactive-protein-in-psoriasis-patients,7,40515,0,1.html
dc.identifier.urihttps://hdl.handle.net/11468/7333
dc.identifier.volume37en_US
dc.identifier.wosWOS:000531068700010
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorUçmak, Derya
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltd.en_US
dc.relation.ispartofPostepy Dermatologii i Alergologii
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMean platelet volumeen_US
dc.subjectNeutrophil-to-lymphocyte ratioen_US
dc.subjectPlatelet-to-lymphocyte ratioen_US
dc.titleThe effect of biological agent treatment on neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, mean platelet volume, and C-reactive protein in psoriasis patientsen_US
dc.titleThe effect of biological agent treatment on neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, mean platelet volume, and C-reactive protein in psoriasis patients
dc.typeArticleen_US

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