The Role of Apparent Diffusion Coefficient Quantification in Differentiating Benign and Malignant Renal Masses by 3 Tesla Magnetic Resonance Imaging

dc.contributor.authorGoya, Cemil
dc.contributor.authorHamidi, Cihad
dc.contributor.authorBozkurt, Yasar
dc.contributor.authorYavuz, Alpaslan
dc.contributor.authorKuday, Suzan
dc.contributor.authorGumus, Hatice
dc.contributor.authorTurkcu, Gul
dc.date.accessioned2024-04-24T17:25:05Z
dc.date.available2024-04-24T17:25:05Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Diffusion-weighted magnetic resonance imaging (DWI) is a widely-accepted diagnostic modality whose efficacy has been investigated by numerous past studies in the differentiation of malignant lesions from benign entities. Aims: The aim of this study was to evaluate the efficiency of diffusion-weighted magnetic resonance imaging in the characterization of renal lesions. Study Design: Diagnostic accuracy study. Methods: A total of 137 patients with renal lesions were included in this study. The median apparent diffusion coefficient (ADC) values as well as the b 800 and b 1600 signal intensities of normal kidneys, solid components of mixed renal masses, and total cystic lesions were evaluated. Results: There were significant differences between the ADC values of lesions and normal renal parenchyma, and between the ADC values of benign and malignant renal lesions on DWIs at b values of 800 and 1600 s/mm(2) (p<0.001 and p<0.001, respectively). There were significant differences between the ADC values of Bosniak Category 1 and 2 cysts and the ADC values of Bosniak Category 1 and 3 cysts on DWIs at b values of 800 s/mm(2) (p<0.001) and 1600 s/mm(2) (p<0.001). A cutoff value of 1.902 x 10(-3) mm(2)/s for the ADC with a b value of 800 s/mm(2) provided 88% sensitivity and 96% specificity for differentiation between benign and malignant renal lesions. A cutoff value of 1.623 x 10(-3) mm(2)/s for the ADC with a b value of 1600 s/mm(2) provided 79% sensitivity and 96% specificity (p<0.001) for the differentiation between benign and malignant renal lesions. Conclusion: Accurate assessment of renal masses is important for determining the necessity for surgical intervention. DWI provides additional value by differentiating benign from malignant renal tumors and can be added to routine kidney MRI protocols.en_US
dc.identifier.doi10.5152/balkanmedj.2015.15475
dc.identifier.endpage278en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue3en_US
dc.identifier.pmid26185715
dc.identifier.startpage273en_US
dc.identifier.trdizinid173624
dc.identifier.urihttps://doi.org/10.5152/balkanmedj.2015.15475
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/173624
dc.identifier.urihttps://hdl.handle.net/11468/19928
dc.identifier.volume32en_US
dc.identifier.wosWOS:000357330600006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofBalkan Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectApparent Diffusion Coefficienten_US
dc.subjectDiffusion-Weighted Magnetic Resonance Imagingen_US
dc.subjectRenal Neoplasmsen_US
dc.subject3 T Mrien_US
dc.titleThe Role of Apparent Diffusion Coefficient Quantification in Differentiating Benign and Malignant Renal Masses by 3 Tesla Magnetic Resonance Imagingen_US
dc.titleThe Role of Apparent Diffusion Coefficient Quantification in Differentiating Benign and Malignant Renal Masses by 3 Tesla Magnetic Resonance Imaging
dc.typeArticleen_US

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