Genetic polymorphisms of Cyp19 and myostatin genes in Turkish indigenous sheep breeds

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dc.authorid0000-0001-7330-103Xen_US
dc.authorid0000-0002-1595-2827en_US
dc.authorid0000-0002-2779-1098en_US
dc.authorid0000-0002-9013-930Xen_US
dc.authorid0000-0003-0702-6660en_US
dc.contributor.authorAkış, Iraz
dc.contributor.authorGürsel, Feraye Esen
dc.contributor.authorÇakmak, Neziha Hacıhasanoğlu
dc.contributor.authorAtmaca, Gizem
dc.contributor.authorYardibi, Hasret
dc.contributor.authorAteş, Atila
dc.contributor.authorDurak, Mehmet Hanifi
dc.date.accessioned2024-03-26T13:03:36Z
dc.date.available2024-03-26T13:03:36Z
dc.date.issued2017en_US
dc.departmentDicle Üniversitesi, Veteriner Fakültesi, Temel Bilimler Bölümü, Biyokimya Ana Bilim Dalıen_US
dc.description.abstractGrowth and meat production traits are very important in sheep breeding. Cyp19 gene has a major role in reproductive activity and growth due to its function in estrogen synthesis. Another gene affecting growth traits is Myostatin (MSTN) gene, which mainly regulates skeletal muscle growth. In this study allele frequencies of genetic polymorphism in Cyp19 and Myostatin genes were identified by PCR-RFLP method in five indigenous Turkish sheep breeds, Chiose, Imroz, Kivircik, Zom and Morkaraman. Digestion of Cyp19 gene with HaeIII only revealed uncut AA genotype and digestion of MSTN with DraI also revealed only uncut AA genotype. Both loci analyzed in this study were found to be monomorphic in five Turkish indigenous sheep breeds. These highly conserved parts of the two genes can be useful for molecular evolutionary studies in sheep. Further studies regarding association analysis of Cyp19 and MSTN in sheep should be conducted.en_US
dc.identifier.citationAkış, I., Gürsel, F. E., Çakmak, N. H., Atmaca, G., Yardibi, H., Ateş, A. ve diğerleri.(2017). Genetic polymorphisms of Cyp19 and myostatin genes in Turkish indigenous sheep breeds. Journal of the Hellenic Veterinary Medical Society, 68(3), 313-318.en_US
dc.identifier.doi10.12681/jhvms.15475
dc.identifier.endpage318en_US
dc.identifier.issn1792-2720
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85042564837
dc.identifier.scopusqualityQ4
dc.identifier.startpage313en_US
dc.identifier.urihttps://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/15475
dc.identifier.urihttps://hdl.handle.net/11468/13736
dc.identifier.volume68en_US
dc.identifier.wosWoSIDEksik
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorDurak, Mehmet Hanifi
dc.language.isoenen_US
dc.publisherHellenic Veterinary Medical Societyen_US
dc.relation.ispartofJournal of the Hellenic Veterinary Medical Society
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCyp19en_US
dc.subjectMyostatinen_US
dc.subjectPCR-RFLPen_US
dc.subjectSheepen_US
dc.subjectSNPen_US
dc.titleGenetic polymorphisms of Cyp19 and myostatin genes in Turkish indigenous sheep breedsen_US
dc.titleGenetic polymorphisms of Cyp19 and myostatin genes in Turkish indigenous sheep breeds
dc.typeArticleen_US

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