Association between cupular deposits and otosclerosis

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dc.contributor.authorHayashi, Hideo
dc.contributor.authorCüreoǧlu, Sebahattin
dc.contributor.authorSchachern, Patricia A.
dc.contributor.authorOktay, Mehmet Faruk
dc.contributor.authorFukushima, Hisaki
dc.contributor.authorSone, Michihiko
dc.contributor.authorPaparella, Michael Mauro
dc.contributor.orcid0000-0001-9220-7073
dc.contributor.orcid0000-0001-7380-610X
dc.date.accessioned2024-04-24T15:59:17Z
dc.date.available2024-04-24T15:59:17Z
dc.date.issued2006
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak, Burun ve Boğaz Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractObjective: To evaluate whether otosclerosis is an underlying mechanism for the production of cupular deposits and to study the association between cupular deposits and dysequilibrium in otosclerosis. Design: Retrospective human temporal bone (TB) study. The incidence of cupular deposits in these 70 TBs was analyzed. Correlations between cupular deposits and vestibular symptoms, endosteal involvement of the otosclerotic focus, stapedial fixation, and clinical history of stapes surgery were evaluated. Setting: Otolaryngology laboratory in a tertiary academic medical center. Patients: The study material consisted of 35 human TBs with otosclerosis and 35 age-matched controls. Main Outcome Measures: Morphometric evaluations of the incidence of cupular deposits, endosteal involvement of the otosclerotic focus, and stapedial fixation were made by light microscopy. Clinical records were reviewed retrospectively for clinical history of stapes surgery and prevalence of vestibular symptoms. The incidence of cupular deposits was compared between the otosclerotic and control groups. Correlations between cupular deposits and vestibular symptoms, endosteal involvement of the otosclerotic focus, stapedial fixation, and clinical history of stapes surgery were evaluated in the subjects with otosclerosis. Results: The incidence of cupular deposits in TBs with otosclerosis was significantly higher than in those without whereas there was no correlation between the incidence of the deposits and dysequilibrium in cases of otosclerosis. An increase in deposits did not correlate with stapedial fixation, stapes surgery, or endosteal involvement. Conclusions: Our results suggest otosclerosis as an underlying mechanism for the production of cupular deposits; however, we did not find an association between these deposits and vestibular symptoms.en_US
dc.identifier.citationHayashi, H., Cüreoğlu, S., Schachern, P. A., Oktay, M. F., Fukushima, H., Sone, M. ve diğerleri. (2006). Association between cupular deposits and otosclerosis. Archives of Otolaryngology - Head and Neck Surgery, 132(12), 1331-1334.
dc.identifier.doi10.1001/archotol.132.12.1331
dc.identifier.endpage1334en_US
dc.identifier.issn0886-4470
dc.identifier.issn1538-361X
dc.identifier.issue12en_US
dc.identifier.pmid17178944
dc.identifier.scopus2-s2.0-33845680803
dc.identifier.scopusqualityN/A
dc.identifier.startpage1331en_US
dc.identifier.urihttps://doi.org/10.1001/archotol.132.12.1331
dc.identifier.urihttps://hdl.handle.net/11468/13938
dc.identifier.volume132en_US
dc.identifier.wosWOS:000242769900007
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorOktay, Mehmet Faruk
dc.language.isoenen_US
dc.publisherAmer Medical Assocen_US
dc.relation.ispartofArchives of Otolaryngology - Head and Neck Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleAssociation between cupular deposits and otosclerosisen_US
dc.titleAssociation between cupular deposits and otosclerosis
dc.typeArticleen_US

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