Evaluation of the effect of obstructive sleep apnea syndrome on retinal microvascularity by optical coherence tomography angiography

dc.authorid0000-0001-8856-0528en_US
dc.authorid0000-0001-5742-1293en_US
dc.authorid0000-0002-3591-721Xen_US
dc.authorid0000-0003-3346-3290en_US
dc.authorid0000-0002-8206-781Xen_US
dc.authorid0000-0002-2597-6646en_US
dc.authorid0000-0003-2348-4856en_US
dc.contributor.authorAva, Sedat
dc.contributor.authorErdem, Seyfettin
dc.contributor.authorKarahan, Mine
dc.contributor.authorDursun, Mehmet Emin
dc.contributor.authorHazar, Leyla
dc.contributor.authorŞen, Hadice Selimoğlu
dc.contributor.authorKeklikçi, Uğur
dc.date.accessioned2023-04-05T08:14:34Z
dc.date.available2023-04-05T08:14:34Z
dc.date.issued2022en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göz Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractPurpose: Using optical coherence tomography angiography (OCTA), we sought to determine whether there are retinal microvascular changes in patients with obstructive sleep apnea syndrome (OSAS). Method: The study included 56 patients diagnosed with OSAS by polysomnography [21 patients with mild OSAS (group 1), 14 with moderate OSAS (group 2) and 21 with severe OSAS (group 3)], and 26 healthy individuals as a control group (group 4). The vascular densities of the superficial capillary plexus and deep capillary plexus of the retinal segmentations, together with the foveal avascular zone (FAZ) width, were measured for all participants, using OCTA.Result: Compared with the control group, vascular densitiy in whole image of superficial capillary plexus were found to be significantly lower in group 2. In addition, vascular densitiy in fovea region of superficial capillary plexus was significantly lower in group 1 than the control group. In deep capillary plexus, vascular densitiy of whole image, superior hemi and nasal regions were found to be significantly lower in group 2 and group 3 compared with the control group. Parafoveal region in group 3 had significantly lower vascular densities than the controls. A significantly larger FAZ was also found in group 1 and group 3 in the deep capillary plexus, compared with the controls. Conclusion: We detected smaller vascular densities in both the superficial capillary plexus and deep capillary plexus and a larger deep capillary plexus FAZ in OSAS patients. Therefore, OCTA may be useful as a non-invasive method to understand the systemic effects of OSAS.en_US
dc.identifier.citationAva, S., Erdem, S., Karahan, M., Dursun, M.E., Hazar, L., Şen, H.S. ve diğerleri. (2022). Evaluation of the effect of obstructive sleep apnea syndrome on retinal microvascularity by optical coherence tomography angiography. Photodiagnosis and Photodynamic Therapy, 38,102761.en_US
dc.identifier.doi10.1016/j.pdpdt.2022.102761
dc.identifier.endpage5en_US
dc.identifier.issn1572-1000
dc.identifier.issn1873-1597
dc.identifier.pmid35181509
dc.identifier.scopus2-s2.0-85127047380
dc.identifier.scopusqualityQ1
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S1572100022000503?via%3Dihub
dc.identifier.urihttps://hdl.handle.net/11468/11606
dc.identifier.volume38en_US
dc.identifier.wosWOS:000791316500003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAva, Sedat
dc.institutionauthorErdem, Seyfettin
dc.institutionauthorKarahan, Mine
dc.institutionauthorDursun, Mehmet Emin
dc.institutionauthorHazar, Leyla
dc.institutionauthorŞen, Hadice Selimoğlu
dc.institutionauthorKeklikçi, Uğur
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofPhotodiagnosis and Photodynamic Therapy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOptical coherence tomography angiographyen_US
dc.subjectObstructive sleep apnea syndromeen_US
dc.subjectSuperficial capillary plexusen_US
dc.subjectDeep capillary plexusen_US
dc.subjectVascular densitiyseen_US
dc.titleEvaluation of the effect of obstructive sleep apnea syndrome on retinal microvascularity by optical coherence tomography angiographyen_US
dc.titleEvaluation of the effect of obstructive sleep apnea syndrome on retinal microvascularity by optical coherence tomography angiography
dc.typeArticleen_US

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