Efficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients
dc.contributor.author | Tamam, Yusuf | |
dc.contributor.author | Özdemir, Hasan Hüseyin | |
dc.contributor.author | Gedik, Abdullah | |
dc.contributor.author | Tamam, Cüneyt | |
dc.contributor.author | Nazlıkul, Hüseyin | |
dc.date.accessioned | 2024-04-24T15:59:30Z | |
dc.date.available | 2024-04-24T15:59:30Z | |
dc.date.issued | 2017 | |
dc.department | Dicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalı | en_US |
dc.description.abstract | AimsMany agents and treatments are used in the treatment of neurogenic detrusor overactivity (NDO) in MS patients, but no study has been conducted on the use of peripheric lidocaine (neural therapyNT) on MS patients. We evaluated the effects of local administration of lidocaine on NDO in Multiple Sclerosis (MS) patients. MethodsFor each patient local anesthetic lidocaine was injected at each session. Sessions were held once a week for 5 weeks. At each session, Th 10-L1, urogenital segment intradermal injections, Frankenhauser, and sacral epidural injections were given. The patients had clinical and urodynamic assessment 1 month before and 3, 9, and 12 months after NT. In addition, multiple sclerosis quality of life inventory (MSQL-54) and bladder control scale (BLCS) was performed for patients. ResultsTwenty-eight patients were included in the study (8 males, 20 females). The patients' average age was 31.78.1 years. The injection therapy significantly improved volume at first involuntary bladder contraction (FCV), maximal detrusor pression during filling (P det. max.), maximal cystometric bladder capacity (MCC) after 3 months. Also, the MSQL-54 and BLCS scores were improved with treatment. However, these improvements reached a maximum 3 months after treatment, but from the 9 month a regression was seen in the parameters, and after 12 months the findings were seen to be slightly above their basal levels. ConclusionsThese results suggest that NDO treatment in MS patients could be an effective treatment which is easy and has very few side effects, and is cost effective. | en_US |
dc.identifier.citation | Tamam, Y., Özdemir, H. H., Gedik, A., Tamam, C. ve Nazlıkul, H. (2017). Efficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients. Neurourology and Urodynamics, 36(7), 1832-1838. | |
dc.identifier.doi | 10.1002/nau.23191 | |
dc.identifier.endpage | 1838 | en_US |
dc.identifier.issn | 0733-2467 | |
dc.identifier.issn | 1520-6777 | |
dc.identifier.issue | 7 | en_US |
dc.identifier.pmid | 28084625 | |
dc.identifier.scopus | 2-s2.0-85027863706 | |
dc.identifier.scopusquality | Q2 | |
dc.identifier.startpage | 1832 | en_US |
dc.identifier.uri | https://doi.org/10.1002/nau.23191 | |
dc.identifier.uri | https://hdl.handle.net/11468/14109 | |
dc.identifier.uri | https://onlinelibrary.wiley.com/doi/10.1002/nau.23191 | |
dc.identifier.volume | 36 | en_US |
dc.identifier.wos | WOS:000408229600022 | |
dc.identifier.wosquality | Q1 | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.indekslendigikaynak | PubMed | |
dc.language.iso | en | en_US |
dc.publisher | Wiley | en_US |
dc.relation.ispartof | Neurourology and Urodynamics | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Incontinence | en_US |
dc.subject | Lidocaine | en_US |
dc.subject | Multiple sclerosis | en_US |
dc.subject | Neural therapy | en_US |
dc.subject | Neurogenic detrusor overactivity | en_US |
dc.title | Efficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients | en_US |
dc.title | Efficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients | |
dc.type | Article | en_US |
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