Efficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients

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dc.contributor.authorTamam, Yusuf
dc.contributor.authorÖzdemir, Hasan Hüseyin
dc.contributor.authorGedik, Abdullah
dc.contributor.authorTamam, Cüneyt
dc.contributor.authorNazlıkul, Hüseyin
dc.date.accessioned2024-04-24T15:59:30Z
dc.date.available2024-04-24T15:59:30Z
dc.date.issued2017
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalıen_US
dc.description.abstractAimsMany agents and treatments are used in the treatment of neurogenic detrusor overactivity (NDO) in MS patients, but no study has been conducted on the use of peripheric lidocaine (neural therapyNT) on MS patients. We evaluated the effects of local administration of lidocaine on NDO in Multiple Sclerosis (MS) patients. MethodsFor each patient local anesthetic lidocaine was injected at each session. Sessions were held once a week for 5 weeks. At each session, Th 10-L1, urogenital segment intradermal injections, Frankenhauser, and sacral epidural injections were given. The patients had clinical and urodynamic assessment 1 month before and 3, 9, and 12 months after NT. In addition, multiple sclerosis quality of life inventory (MSQL-54) and bladder control scale (BLCS) was performed for patients. ResultsTwenty-eight patients were included in the study (8 males, 20 females). The patients' average age was 31.78.1 years. The injection therapy significantly improved volume at first involuntary bladder contraction (FCV), maximal detrusor pression during filling (P det. max.), maximal cystometric bladder capacity (MCC) after 3 months. Also, the MSQL-54 and BLCS scores were improved with treatment. However, these improvements reached a maximum 3 months after treatment, but from the 9 month a regression was seen in the parameters, and after 12 months the findings were seen to be slightly above their basal levels. ConclusionsThese results suggest that NDO treatment in MS patients could be an effective treatment which is easy and has very few side effects, and is cost effective.en_US
dc.identifier.citationTamam, Y., Özdemir, H. H., Gedik, A., Tamam, C. ve Nazlıkul, H. (2017). Efficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients. Neurourology and Urodynamics, 36(7), 1832-1838.
dc.identifier.doi10.1002/nau.23191
dc.identifier.endpage1838en_US
dc.identifier.issn0733-2467
dc.identifier.issn1520-6777
dc.identifier.issue7en_US
dc.identifier.pmid28084625
dc.identifier.scopus2-s2.0-85027863706
dc.identifier.scopusqualityQ2
dc.identifier.startpage1832en_US
dc.identifier.urihttps://doi.org/10.1002/nau.23191
dc.identifier.urihttps://hdl.handle.net/11468/14109
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/nau.23191
dc.identifier.volume36en_US
dc.identifier.wosWOS:000408229600022
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofNeurourology and Urodynamics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIncontinenceen_US
dc.subjectLidocaineen_US
dc.subjectMultiple sclerosisen_US
dc.subjectNeural therapyen_US
dc.subjectNeurogenic detrusor overactivityen_US
dc.titleEfficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patientsen_US
dc.titleEfficacy of peripheral lidocaine application (neural therapy) in the treatment of neurogenic detrusor overactivity in multiple sclerosis patients
dc.typeArticleen_US

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