Epidemiological and clinical characteristics of malignant melanoma in Southeast Anatolia in Turkey

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dc.contributor.authorSula, Bilal
dc.contributor.authorUcmak, Feyzullah
dc.contributor.authorKaplan, Mehmet Ali
dc.contributor.authorUrakci, Zuhat
dc.contributor.authorArica, Mustafa
dc.contributor.authorIsikdogan, Abdurrahman
dc.date.accessioned2024-04-24T17:14:30Z
dc.date.available2024-04-24T17:14:30Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction: The present study aimed to establish the epidemiological and clinical characteristics of patients who were histopathologically diagnosed with malignant melanoma (MM). Methods: The present study retrospectively analyzed the data of 78 patients who were histopathologically diagnosed with MM in Dicle University Medical Faculty, Dermatology and Medical Oncology departments between 2005 and 2014. Results: The study included 78 patients in total with 44 (56.4%) male and 34 (43.6%) female. Median age of the patients was 62.50 years (range: 27 - 84 years). Of the patients, 78.2% (n=61) had cutaneous melanoma, 8.9% had solid organ melanoma, and 2.5% had ocular and mucosal melanoma. The most common tumor localization among the patients was the lower extremities with 29.4% (n=23). The most common histopathological type was nodular malignant melanoma with 35.8% (n=28). Based on TNM, Clark and Breslow classifications, 26.9% (n=21) of the patients were stage 4, 26.9% (n=21) were Clark stage 4, and 37.1% (n=29) were Breslow stage 4. Median overall survival in all patients was 14.9 months (95% CI 10.9 - 18.8 months). In the multivariate Cox analysis, only stage statistically significantly affecting survival [ odds ratio (OR): 0.54; (95% CI 0.16-1.82, p=0.02)]. Conclusion: Malignant melanoma data are also important for the optimal utilization of effective methods and healthcare resources to prevent the disease. In order to minimize MM mortality and morbidity, not only the society but also physicians from primary and secondary care hospitals should become familiar with melanoma.en_US
dc.identifier.doi10.11604/pamj.2016.24.22.9254
dc.identifier.issn1937-8688
dc.identifier.pmid27583086
dc.identifier.scopus2-s2.0-84975460804
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.11604/pamj.2016.24.22.9254
dc.identifier.urihttps://hdl.handle.net/11468/18002
dc.identifier.volume24en_US
dc.identifier.wosWOS:000377007300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherAfrican Field Epidemiology Network-Afeneten_US
dc.relation.ispartofPan African Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMalignant Melanomaen_US
dc.subjectClinicen_US
dc.subjectEpidemiologyen_US
dc.titleEpidemiological and clinical characteristics of malignant melanoma in Southeast Anatolia in Turkeyen_US
dc.titleEpidemiological and clinical characteristics of malignant melanoma in Southeast Anatolia in Turkey
dc.typeArticleen_US

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