Effects of different doses of oral ketamine for premedication of children

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dc.contributor.authorTurhanoglu, S
dc.contributor.authorKararmaz, A
dc.contributor.authorÖzyilmaz, MA
dc.contributor.authorKaya, S
dc.contributor.authorTok, D
dc.date.accessioned2024-04-24T17:08:09Z
dc.date.available2024-04-24T17:08:09Z
dc.date.issued2003
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground and objective: A need exists for a safe and effective oral preanaesthetic medication for use in children undergoing elective surgery. The study sought to define the dose of oral ketamine that would facilitate induction of anaesthesia without causing significant side-effects. Methods: We studied 80 children undergoing elective surgery under general anaesthesia who received oral ketamine 4, 6 or 8 mg kg(-1) in a prospective, randomized, double-blind placebo controlled study. We compared the reaction to separation from parents, transport to the operating room, the response to intravenous cannula insertion and application of an anaesthetic facemask, the induction of anaesthesia and recovery from anaesthesia, Results: In the group receiving ketamine 8 mg kg(-1), the children were significantly calmer than those of the other groups, and anaesthesia induction was more comfortable. Recovery from anaesthesia was longer in the group receiving ketamine 8 mg kg(-1) compared with the other groups, but no differences between the groups were observed after 2 h in the recovery room. Conclusions: It is concluded that oral ketamine 8 mg kg is an effective oral premedication in inpatient children undergoing elective surgery.en_US
dc.identifier.doi10.1097/00003643-200301000-00010
dc.identifier.endpage60en_US
dc.identifier.issn0265-0215
dc.identifier.issue1en_US
dc.identifier.pmid12553389
dc.identifier.scopus2-s2.0-0037228298
dc.identifier.scopusqualityQ1
dc.identifier.startpage56en_US
dc.identifier.urihttps://doi.org/10.1097/00003643-200301000-00010
dc.identifier.urihttps://hdl.handle.net/11468/17228
dc.identifier.volume20en_US
dc.identifier.wosWOS:000180664000010
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherGreenwich Medical Media Ltden_US
dc.relation.ispartofEuropean Journal of Anaesthesiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnaesthetics, Intravenous, Anaesthetics, Dissociative, Ketamineen_US
dc.subjectPaediatricsen_US
dc.subjectPremedicationen_US
dc.titleEffects of different doses of oral ketamine for premedication of childrenen_US
dc.titleEffects of different doses of oral ketamine for premedication of children
dc.typeArticleen_US

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