Phytochemical composition, antimicrobial, antioxidant, and wound healing activities of Thermopsis turcica

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dc.authoridAksoy, Lacine/0000-0001-8086-5079
dc.authoridYILMAZ, Mustafa Abdullah/0000-0002-4090-7227
dc.contributor.authorAkdag, Gulcin
dc.contributor.authorHazman, Omer
dc.contributor.authorAksoy, Lacine
dc.contributor.authorSavrik, Mehmet
dc.contributor.authorBuyukben, Ahmet
dc.contributor.authorYilmaz, Mustafa Abdullah
dc.contributor.authorCakir, Oguz
dc.date.accessioned2025-02-22T14:08:48Z
dc.date.available2025-02-22T14:08:48Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe antioxidant, antimicrobial, anticarcinogenic, wound healing activities and phenolic substance profile of aqueous extracts prepared using branch, leaf, flower parts and above-ground parts of Thermopsis turcica were determined in the study. The analyses indicate that the total phenolic substance contents and total antioxidant status are higher in the mix, flower, and leaf extracts. The extracts reduced cell viability in HGF cells more than in A549 cells. It shows that the extract has low anticarcinogenic activity in A549 cells. Flower extract had the highest wound closure rate. Quinic acid, cyranoside and luteolin were found in high concentrations in all extracts with LC/ESI-MS/LC analysis. It has been determined that the flower extract of the species is the most critical part showing antioxidant, antimicrobial, cytotoxic and wound healing properties. While the leaf and mix extracts stand out with their antioxidative and antimicrobial properties, the branch extract is effective in wound healing.en_US
dc.description.sponsorshipScientific Research Project Fund of Afyon Kocatepe University (AKU-BAP) [23.FEN.BIL.02]en_US
dc.description.sponsorshipThis work is supported by the Scientific Research Project Fund of Afyon Kocatepe University (AKU-BAP) under the Project number 23.FEN.BIL.02.en_US
dc.identifier.doi10.1515/znc-2024-0102
dc.identifier.issn0939-5075
dc.identifier.issn1865-7125
dc.identifier.pmid39422443en_US
dc.identifier.scopus2-s2.0-85207565308en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1515/znc-2024-0102
dc.identifier.urihttps://hdl.handle.net/11468/29645
dc.identifier.wosWOS:001338960000001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofZeitschrift Fur Naturforschung Section C-A Journal of Biosciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectThermopsis turcicaen_US
dc.subjectantioxidanten_US
dc.subjectantimicrobialen_US
dc.subjectcytotoxicen_US
dc.subjectwound healingen_US
dc.titlePhytochemical composition, antimicrobial, antioxidant, and wound healing activities of Thermopsis turcicaen_US
dc.typeArticleen_US

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