Non-Hodgkin's lymphoma in southeast Turkey: clinicopathologic features of 490 cases

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dc.contributor.authorIsikdogan, A
dc.contributor.authorAyyildiz, O
dc.contributor.authorBuyukcelik, A
dc.contributor.authorArslan, A
dc.contributor.authorTiftik, N
dc.contributor.authorBuyukbayram, H
dc.contributor.authorMuftuoglu, E
dc.date.accessioned2024-04-24T16:00:01Z
dc.date.available2024-04-24T16:00:01Z
dc.date.issued2004
dc.departmentDicle Üniversitesien_US
dc.description.abstractWe have carried out a retrospective analysis of 490 non-Hodakin's lymphomas (NHLS), followed at our clinic, with the purpose of evaluating the clinicopathologic features of these patients. The patients were assessed with regard to their characteristics including age gender. histologic distribution, stage, extranodal involvement. presenting symptoms, and biopsied site. Of the patients 314 (64%) were male and 176 (36%) were female. The overall median age was 43 years (range: 1490). The patients were classified according to the Working Formulation (WF) system: 71 (14.4%) were low grade, 342 (69.8%) were intermediate grade, 43 (8.7%) were high grade, and 34 (6.7%) had other lymphomas. Intermediate-grade non-Hodgkin's lymphomas formed the largest group, of whom 320 patients' paraffin blocks were available for Revised European and American lymphoma (REAL) classification: 78% were B-cell lymphomas, whereas 16% were T/NK lymphomas. Six percent of cases were unclassified lymphomas. Diffuse large B-cell lymphoma (DLBCL) was the most commonly observed histopathologic type in 132 (41%) patients. Extranodal involvement was found in 218 (44.5%) patients. The most commonly affected extranodal sites were small bowel, stomach, and tonsil in 72 (33%), 63 (29%), and 19 (8.7%) patients, respectively. According to the Ann Arbor staging system, the vast majority of patients (89.4%) were advanced stage. In conclusion, the characteristics of NHLs in our region show some differences from the other sites of Turkey and the world.en_US
dc.identifier.doi10.1007/s00277-003-0812-0
dc.identifier.endpage269en_US
dc.identifier.issn0939-5555
dc.identifier.issn1432-0584
dc.identifier.issue5en_US
dc.identifier.pmid15060744
dc.identifier.scopus2-s2.0-2342544072
dc.identifier.scopusqualityQ2
dc.identifier.startpage265en_US
dc.identifier.urihttps://doi.org/10.1007/s00277-003-0812-0
dc.identifier.urihttps://hdl.handle.net/11468/14346
dc.identifier.volume83en_US
dc.identifier.wosWOS:000221038200001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAnnals of Hematology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNon-Hodgkin's Lymphomaen_US
dc.subjectEpidemiologyen_US
dc.subjectHistologic Subtypeen_US
dc.subjectExtranodal Involvementen_US
dc.titleNon-Hodgkin's lymphoma in southeast Turkey: clinicopathologic features of 490 casesen_US
dc.titleNon-Hodgkin's lymphoma in southeast Turkey: clinicopathologic features of 490 cases
dc.typeArticleen_US

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